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本文引用的文献

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Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use.哮喘患儿血清维生素 D 水平降低与皮质类固醇激素用量增加有关。
J Allergy Clin Immunol. 2010 May;125(5):995-1000. doi: 10.1016/j.jaci.2010.03.008. Epub 2010 Apr 9.
2
Vitamin D - a new treatment for airway remodelling in asthma?维生素 D - 哮喘气道重塑的新疗法?
Br J Pharmacol. 2009 Nov;158(6):1426-8. doi: 10.1111/j.1476-5381.2009.00429.x.
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Assessment of vitamin D status and definition of a normal circulating range of 25-hydroxyvitamin D.维生素D状态评估及25-羟维生素D正常循环范围的定义
Curr Opin Endocrinol Diabetes Obes. 2008 Dec;15(6):489-94. doi: 10.1097/MED.0b013e328317ca6c.
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Randomized controlled trial of vitamin D supplementation for winter-related atopic dermatitis in Boston: a pilot study.维生素D补充剂治疗波士顿冬季相关性特应性皮炎的随机对照试验:一项试点研究。
Br J Dermatol. 2008 Jul;159(1):245-7. doi: 10.1111/j.1365-2133.2008.08601.x. Epub 2008 Jul 1.
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Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen).变应性鼻炎及其对哮喘的影响(ARIA)2008年更新版(与世界卫生组织、全球变态反应和哮喘欧洲网络及变应原组合作)
Allergy. 2008 Apr;63 Suppl 86:8-160. doi: 10.1111/j.1398-9995.2007.01620.x.
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Vitamin D deficiency and asthma: not a strong link--yet.维生素D缺乏与哮喘:目前尚无紧密联系。
J Allergy Clin Immunol. 2008 Mar;121(3):782-3; author reply 783-4. doi: 10.1016/j.jaci.2007.12.1170.
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Is vitamin D deficiency to blame for the asthma epidemic?哮喘流行该归咎于维生素D缺乏吗?
J Allergy Clin Immunol. 2007 Nov;120(5):1031-5. doi: 10.1016/j.jaci.2007.08.028. Epub 2007 Oct 24.
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Vitamin D serum levels and allergic rhinitis.血清维生素D水平与过敏性鼻炎
Allergy. 2007 Sep;62(9):1085-6. doi: 10.1111/j.1398-9995.2007.01437.x.
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Trends in the prevalence of asthma symptoms and allergic diseases in Israeli adolescents: results from a national survey 2003 and comparison with 1997.以色列青少年哮喘症状和过敏性疾病患病率的趋势:2003年全国调查结果及与1997年的比较。
J Asthma. 2007 Jun;44(5):365-9. doi: 10.1080/02770900701363983.
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Prevalence of asthma, rhinitis and eczema in 6 - 7 years old students from the western districts of São Paulo City, using the standardized questionnaire of the "International Study of Asthma and Allergies in Childhood" (ISAAC)-phase IIIB.使用“儿童哮喘和过敏国际研究”(ISAAC)第三阶段B的标准化问卷,对圣保罗市西区6至7岁学生的哮喘、鼻炎和湿疹患病率进行调查。
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过敏性鼻炎患者的血清维生素D水平:与正常人群有差异吗?

Vitamin D serum levels in allergic rhinitis: any difference from normal population?

作者信息

Arshi Saba, Ghalehbaghi Babak, Kamrava Seyyed-Kamran, Aminlou Mina

机构信息

Department of Asthma, Allergy and Clinical Immunology, Hazrat Rasoul Akram Hospital, Tehran University of Medical Sciences, Tehran 1445613131, Iran.

出版信息

Asia Pac Allergy. 2012 Jan;2(1):45-8. doi: 10.5415/apallergy.2012.2.1.45. Epub 2012 Jan 18.

DOI:10.5415/apallergy.2012.2.1.45
PMID:22348206
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3269601/
Abstract

BACKGROUND

Recently it has been suggested that, the worldwide increase in allergic diseases such as asthma, allergic rhinitis and food allergy is associated with low vitamin D intake.

OBJECTIVE

This study measured the vitamin D levels in patients with allergic rhinitis and compared the results with the general population.

METHODS

Vitamin D levels were assessed in 50 patients with allergic rhinitis diagnosed clinically by Allergic Rhinitis and its Impact on Asthma 2008 criteria and the result of skin prick test for aeroallergens. There was no control group, and the study results were compared with the results of another study evaluating vitamin D status in the 5,329 people of normal population of Iran.

RESULTS

The prevalence of severe vitamin D deficiency was significantly higher in patients with allergic rhinitis than the normal population, 30% and 5.1% respectively (p = 0.03). Also women with allergic rhinitis had lower vitamin D levels.

CONCLUSION

Measuring vitamin D serum levels could be helpful in the routine assessment of patients with allergic rhinitis in Iran.

摘要

背景

最近有人提出,全球范围内哮喘、过敏性鼻炎和食物过敏等过敏性疾病的增加与维生素D摄入量低有关。

目的

本研究测量了过敏性鼻炎患者的维生素D水平,并将结果与普通人群进行比较。

方法

根据《过敏性鼻炎及其对哮喘的影响2008标准》对50例临床诊断为过敏性鼻炎的患者进行维生素D水平评估,并对气传变应原进行皮肤点刺试验。没有对照组,研究结果与另一项评估伊朗5329名正常人群维生素D状况的研究结果进行比较。

结果

过敏性鼻炎患者中严重维生素D缺乏的患病率显著高于正常人群,分别为30%和5.1%(p = 0.03)。此外,患有过敏性鼻炎的女性维生素D水平较低。

结论

测量血清维生素D水平可能有助于伊朗过敏性鼻炎患者的常规评估。