Vitamin D deficiency and asthma: not a strong link--yet.
作者信息
Schauber Jürgen, Gallo Richard L
出版信息
J Allergy Clin Immunol. 2008 Mar;121(3):782-3; author reply 783-4. doi: 10.1016/j.jaci.2007.12.1170.
Abstract
摘要
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Is vitamin D deficiency to blame for the asthma epidemic?哮喘流行该归咎于维生素D缺乏吗？
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2
An association of serum vitamin D concentrations < 40 nmol/L with acute respiratory tract infection in young Finnish men.芬兰年轻男性血清维生素D浓度<40 nmol/L与急性呼吸道感染之间的关联。
Am J Clin Nutr. 2007 Sep;86(3):714-7. doi: 10.1093/ajcn/86.3.714.
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Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.丝氨酸蛋白酶活性增加和cathelicidin会促进酒渣鼻的皮肤炎症。
Nat Med. 2007 Aug;13(8):975-80. doi: 10.1038/nm1616. Epub 2007 Aug 5.
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Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism.损伤通过维生素D依赖机制增强TLR2功能和抗菌肽表达。
J Clin Invest. 2007 Mar;117(3):803-11. doi: 10.1172/JCI30142. Epub 2007 Feb 8.
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Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.Toll样受体触发维生素D介导的人类抗菌反应。
Science. 2006 Mar 24;311(5768):1770-3. doi: 10.1126/science.1123933. Epub 2006 Feb 23.
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Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns.维生素D3下调单核细胞Toll样受体（TLR）的表达，并引发对病原体相关分子模式的低反应性。
Eur J Immunol. 2006 Feb;36(2):361-70. doi: 10.1002/eji.200425995.
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Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system.维生素D状态、1,25-二羟维生素D3与免疫系统。
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