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基于社区的参与式研究以增强少数民族临床试验的系统评价。

A systematic review of community-based participatory research to enhance clinical trials in racial and ethnic minority groups.

机构信息

Commonwealth Fund/Harvard University Fellowship in Minority Health Policy, 164 Longwood Avenue, 2nd Floor, Boston, MA 02115, USA.

出版信息

Health Serv Res. 2012 Jun;47(3 Pt 2):1363-86. doi: 10.1111/j.1475-6773.2012.01386.x. Epub 2012 Feb 21.

DOI:10.1111/j.1475-6773.2012.01386.x
PMID:22353031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3418827/
Abstract

OBJECTIVE

To examine the effectiveness of current community-based participatory research (CBPR) clinical trials involving racial and ethnic minorities.

DATA SOURCE

All published peer-reviewed CBPR intervention articles in PubMed and CINAHL databases from January 2003 to May 2010.

STUDY DESIGN

We performed a systematic literature review.

DATA COLLECTION/EXTRACTION METHODS: Data were extracted on each study's characteristics, community involvement in research, subject recruitment and retention, and intervention effects.

PRINCIPLE FINDINGS

We found 19 articles meeting inclusion criteria. Of these, 14 were published from 2007 to 2010. Articles described some measures of community participation in research with great variability. Although CBPR trials examined a wide range of behavioral and clinical outcomes, such trials had very high success rates in recruiting and retaining minority participants and achieving significant intervention effects.

CONCLUSIONS

Significant publication gaps remain between CBPR and other interventional research methods. CBPR may be effective in increasing participation of racial and ethnic minority subjects in research and may be a powerful tool in testing the generalizability of effective interventions among these populations. CBPR holds promise as an approach that may contribute greatly to the study of health care delivery to disadvantaged populations.

摘要

目的

考察当前涉及少数族裔的基于社区的参与式研究(CBPR)临床试验的效果。

资料来源

2003 年 1 月至 2010 年 5 月期间,在 PubMed 和 CINAHL 数据库中发表的所有同行评审的 CBPR 干预文章。

研究设计

我们进行了系统的文献回顾。

资料收集/提取方法:对每项研究的特征、社区在研究中的参与度、研究对象的招募和保留以及干预效果进行了数据提取。

主要发现

我们找到了符合纳入标准的 19 篇文章。其中,14 篇发表于 2007 年至 2010 年。文章对社区参与研究的一些措施进行了描述,其差异非常大。尽管 CBPR 试验研究了广泛的行为和临床结果,但这些试验在招募和保留少数族裔参与者方面取得了非常高的成功率,并取得了显著的干预效果。

结论

CBPR 与其他干预性研究方法之间仍存在显著的出版差距。CBPR 可能有助于增加少数族裔参与者对研究的参与度,并且可能是在这些人群中测试有效干预措施的可推广性的有力工具。CBPR 有望成为一种方法,为研究向弱势群体提供医疗保健做出巨大贡献。

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