World J Gastroenterol. 2012 Feb 21;18(7):589-600. doi: 10.3748/wjg.v18.i7.589.
Irritable bowel syndrome (IBS) is a functional gut disorder with high prevalence. Because of various factors involved in its pathophysiology and disappointing results from conventional IBS medications, the treatment of IBS is challenging and use of complementary and alternative medicines especially herbal therapies is increasing. In this paper, electronic databases including PubMed, Scopus, and Cochrane library were searched to obtain any in vitro, in vivo or human studies evaluating single or compound herbal preparations in the management of IBS. One in vitro, 3 in vivo and 23 human studies were included and systematically reviewed. The majority of studies are about essential oil of Menta piperita as a single preparation and STW 5 as a compound preparation. Some evaluated herbs such as Curcuma xanthorriza and Fumaria officinalis did not demonstrate any benefits in IBS. However, it seems there are many other herbal preparations such as those proposed in traditional medicine of different countries that could be studied and investigated for their efficacy in management of IBS.
肠易激综合征(IBS)是一种高发的功能性肠道疾病。由于其病理生理学涉及多种因素,以及常规 IBS 药物治疗效果不尽如人意,IBS 的治疗具有挑战性,因此越来越多的人使用补充和替代药物,特别是草药疗法。本文通过电子数据库(包括 PubMed、Scopus 和 Cochrane 图书馆)检索了所有评估单一或复合草药制剂在 IBS 管理中的应用的体外、体内或人体研究。共纳入 1 项体外研究、3 项体内研究和 23 项人体研究,并进行了系统评价。大多数研究是关于胡椒薄荷精油作为单一制剂和 STW 5 作为复合制剂的研究。一些评估草药的研究,如姜黄和罂粟,并没有显示出对 IBS 的任何益处。然而,似乎还有许多其他的草药制剂,如不同国家传统医学中提出的那些制剂,可以对其在 IBS 管理中的疗效进行研究和调查。