埃及鸢尾根茎中的新成分
New constituents from the rhizomes of Egyptian Iris germanica L.
机构信息
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
出版信息
Molecules. 2012 Mar 2;17(3):2587-98. doi: 10.3390/molecules17032587.
Chemical investigation of the methanolic extract of the rhizomes of Iris germanica L. (Iridaceae) afforded two new compounds; irigenin S (7) and iriside A (12), together with ten known compounds: stigmasterol (1), a-irone (2), γ-irone (3), 3-hydroxy-5-methoxyacetophenone (4), irilone (5), irisolidone (6), irigenin (8), stigmasterol-3-O-β-D-glucopyranoside (9), irilone 4'-O-β-D-glucopyranoside (10) and iridin (11). Their structures were established by UV, IR, 1D (¹H and ¹³C) and 2D (¹H-¹H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to mass spectroscopic data and comparison with literature data. The methanolic extract was evaluated for its antimicrobial activity. Both the methanolic extract and the isolated flavonoids were tested for their anti-inflammatory activity.
对鸢尾根茎的甲醇提取物进行化学研究，得到了两种新化合物：鸢尾苷 S（7）和鸢尾苷 A（12），以及 10 种已知化合物：豆甾醇（1）、α-依兰酮（2）、γ-依兰酮（3）、3-羟基-5-甲氧基苯乙酮（4）、依兰酮（5）、鸢尾酮（6）、鸢尾苷（8）、豆甾醇-3-O-β-D-吡喃葡萄糖苷（9）、依兰酮 4'-O-β-D-吡喃葡萄糖苷（10）和鸢尾黄素（11）。它们的结构通过 UV、IR、1D（¹H 和 ¹³C）和 2D（¹H-¹H COSY、HMQC 和 HMBC）NMR 光谱以及质谱数据和与文献数据的比较来确定。评估了甲醇提取物的抗菌活性。甲醇提取物和分离出的类黄酮都进行了抗炎活性测试。
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