Scheithauer B W
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905.
Acta Neuropathol. 1990;80(4):343-54. doi: 10.1007/BF00307686.
The present WHO classification of meningiomas has served us well. In keeping with the adage, "if it ain't broke, don't fix it," alterations should be made with due caution. These proposed modifications of the WHO classification are prompted by advances in our understanding of the pathobiology of meningeal neoplasms, as well as a need for an orderly scheme based upon factors of clinical importance. The author is well aware, that given the vastly differing technologies available to those utilizing the "blue book," its application must have a basis in routine histology rather than in "high-tech" procedures. No classification is ideal, but the modifications suggested represent a compromise between the pathologist's need for a complete morphologic exposition and the clinician's desire for a concise classification of therapeutic and prognostic significance.
世界卫生组织(WHO)目前的脑膜瘤分类一直对我们很有帮助。正如那句格言所说:“如果没坏,就别修。” 因此,进行修改时应谨慎行事。对WHO分类提出这些修改建议,是由于我们对脑膜肿瘤病理生物学的理解取得了进展,同时也需要一个基于具有临床重要性因素的有序方案。作者深知,鉴于使用 “蓝皮书” 的人可利用的技术差异巨大,其应用必须基于常规组织学,而非 “高科技” 程序。没有一种分类是完美的,但所建议的修改是病理学家对完整形态学阐述的需求与临床医生对具有治疗和预后意义的简洁分类的渴望之间的一种折衷。