Department of Psychiatry, University of Cambridge, Herchel Smith Building, Addenbrooke's Hospital, Cambridge CB2 0SZ, UK.
Nat Rev Neurosci. 2012 Mar 14;13(4):279-86. doi: 10.1038/nrn3212.
An increasingly influential perspective conceptualizes both obesity and overeating as a food addiction accompanied by corresponding brain changes. Because there are far-reaching implications for clinical practice and social policy if it becomes widely accepted, a critical evaluation of this model is important. We examine the current evidence for the link between addiction and obesity, identifying several fundamental shortcomings in the model, as well as weaknesses and inconsistencies in the empirical support for it from human neuroscientific research.
一种日益有影响力的观点将肥胖和暴食视为一种伴随着相应大脑变化的食物成瘾。因为如果这一观点被广泛接受,那么它对临床实践和社会政策都有着深远的影响,所以对这一模型进行批判性评估是很重要的。我们考察了成瘾与肥胖之间联系的现有证据,确定了该模型存在几个根本性的缺陷,以及从人类神经科学研究中对其提供的实证支持的弱点和不一致性。