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[Cardiac imaging in (asymptomatic) diabetic patients].

作者信息

Zellweger M J

机构信息

Kardiologische Klinik, Universitätsspital, Petersgraben 4, 4031, Basel, Schweiz.

出版信息

Herz. 2012 May;37(3):252-6. doi: 10.1007/s00059-012-3601-5.

DOI:10.1007/s00059-012-3601-5
PMID:22430285
Abstract

Coronary artery disease (CAD) plays an important role in diabetic patients because they have a very high cardiovascular mortality risk. Therefore the question arises if all diabetic patients should be screened for CAD. In patients with (a)typical angina or anginal equivalents (e.g. shortness of breath) an extended CAD evaluation is indicated. Unselected screening in diabetic patients, however, does not seem to make sense as the only large prospective randomized study in this field did not demonstrate a survival benefit in the screened patient population. It is noteworthy that preoperative risk stratification deserves special consideration in diabetic patients. If screening is considered there is the anatomic approach (calcium score, non-invasive coronary angiography) or the functional approach (stress testing, ischemia evaluation). In diabetic patients who in general should already have all the medication with respect to coronary prevention, functional rather than anatomic testing makes sense because revascularization can be considered in patients with extensive ischemia. In contrast, anatomic testing if positive would only be confirming that a medical preventive strategy is necessary. On the other hand a normal anatomic test has a very high negative predictive value. Therefore, CAD evaluation should follow an individual patient tailored approach as long as evidence-based guidelines are lacking.

摘要

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本文引用的文献

1
Diabetes reduces left ventricular ejection fraction--irrespective of presence and extent of coronary artery disease.糖尿病降低左心室射血分数——与冠状动脉疾病的存在和程度无关。
Eur J Endocrinol. 2011 Dec;165(6):945-51. doi: 10.1530/EJE-11-0687. Epub 2011 Sep 8.
2
Coronary calcium score and prediction of all-cause mortality in diabetes: the diabetes heart study.冠状动脉钙评分与糖尿病全因死亡率的预测:糖尿病心脏研究。
Diabetes Care. 2011 May;34(5):1219-24. doi: 10.2337/dc11-0008. Epub 2011 Mar 11.
3
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执行摘要:2011年糖尿病医疗护理标准
Diabetes Care. 2011 Jan;34 Suppl 1(Suppl 1):S4-10. doi: 10.2337/dc11-S004.
4
Standards of medical care in diabetes--2011.《糖尿病医疗护理标准——2011 年》
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Is diabetic retinopathy related to subclinical cardiovascular disease?糖尿病性视网膜病变与亚临床心血管疾病有关吗?
Ophthalmology. 2011 May;118(5):860-5. doi: 10.1016/j.ophtha.2010.08.040. Epub 2010 Dec 18.
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Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: a position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology.心脏计算机断层扫描和心肌灌注闪烁显像在无症状且无已知心血管疾病的个体中的风险分层:欧洲心脏病学会核心脏病学和心脏 CT 工作组的立场声明。
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