开发一种用于评估阿尔茨海默病患者日常导航能力的问卷，以评估其地形定向障碍。
Development of a questionnaire on everyday navigational ability to assess topographical disorientation in Alzheimer's disease.
机构信息
Division of Behavioral Neurology, Department of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
出版信息
Am J Alzheimers Dis Other Demen. 2012 Feb;27(1):65-72. doi: 10.1177/1533317512436805.
Abstract
We developed a Questionnaire on Everyday Navigational Ability (QuENA) to detect topographical disorientation (TD) in patients with Alzheimer's disease (PwAD). In the QuENA, 3 items were designed to assess landmark agnosia, 2 for egocentric disorientation, 3 for heading disorientation, and 2 for inattention. The PwAD and their caregivers rated QuENA according to which TD symptoms would occur. Regarding the construct validity, confirmatory factor analysis showed that the caregiver version of the QuENA fits the proposed TD model well but the patient version does not. Regarding the internal consistency, the Cronbach's α for the caregiver version was 0.91 and that for the patient version was 0.87. A discrepancy existed between the appraisal of navigational abilities by PwAD and by caregivers, and it was correlated with the number of getting lost (GL) events. The caregiver version of QuENA is a feasible, reliable, and valid instrument to assess TD and it also discriminates well between the PwAD with GL and those without.
摘要
我们开发了一个日常导航能力问卷（QuENA），用于检测阿尔茨海默病患者（PwAD）的地形定向障碍（TD）。在 QuENA 中，设计了 3 个项目来评估地标识别障碍，2 个项目来评估自我中心定向障碍，3 个项目来评估朝向定向障碍，2 个项目来评估注意力不集中。PwAD 和他们的照顾者根据可能出现 TD 症状的情况对 QuENA 进行评分。关于构念效度，验证性因子分析表明，照顾者版本的 QuENA 很好地符合拟议的 TD 模型，但患者版本不符合。关于内部一致性，照顾者版本的 Cronbach's α 为 0.91，患者版本的 Cronbach's α 为 0.87。PwAD 和照顾者对导航能力的评估存在差异，并且与迷路（GL）事件的数量相关。QuENA 的照顾者版本是一种可行、可靠且有效的评估 TD 的工具，它也能很好地区分有 GL 和无 GL 的 PwAD。
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