Department of Pediatrics, University of Colorado, Aurora, Colorado 80045, USA.
J Am Med Inform Assoc. 2012 Jun;19(e1):e36-42. doi: 10.1136/amiajnl-2012-000968. Epub 2012 Apr 20.
Clinical research informatics is the rapidly evolving sub-discipline within biomedical informatics that focuses on developing new informatics theories, tools, and solutions to accelerate the full translational continuum: basic research to clinical trials (T1), clinical trials to academic health center practice (T2), diffusion and implementation to community practice (T3), and 'real world' outcomes (T4). We present a conceptual model based on an informatics-enabled clinical research workflow, integration across heterogeneous data sources, and core informatics tools and platforms. We use this conceptual model to highlight 18 new articles in the JAMIA special issue on clinical research informatics.
临床研究信息学是生物医学信息学中迅速发展的子领域，专注于开发新的信息学理论、工具和解决方案，以加速整个转化过程：从基础研究到临床试验（T1），从临床试验到学术医疗中心实践（T2），从扩散和实施到社区实践（T3），以及“真实世界”结果（T4）。我们提出了一个基于信息学支持的临床研究工作流程、跨异构数据源的集成以及核心信息学工具和平台的概念模型。我们使用这个概念模型来突出 JAMIA 特刊中 18 篇关于临床研究信息学的新文章。
