中国南方地区、和腹泻样本中鼠诺如病毒的流行病学和遗传特征。
Epidemiology and genetic characteristics of murine kobuvirus from faecal samples of , and in southern China.
机构信息
Department of Epidemiology, School of Public Health, Guangdong Provincial Key Laboratory of Tropical Disease Research, Southern Medical University, Guangzhou 510515, PR China.
出版信息
J Gen Virol. 2021 Sep;102(9). doi: 10.1099/jgv.0.001646.
Recently, murine kobuvirus (MuKV), a novel member of the family , was identified in faecal samples of in China. The limited information on the circulation of MuKV in other murine rodent species prompted us to investigate its prevalence and conduct a genetic characterization of MuKV in , and in China. Between 2015 and 2017, 243 faecal samples of these three murine rodent species from three regions in southern China were screened for the presence of MuKV. The overall prevalence was 23.0% (56/243). Three complete MuKV polyprotein sequences were acquired, and the genome organization was determined. Phylogenetic analyses suggested that our sequences were closely related to Chinese strains and belong to the species in the genus . Additional studies are required to understand the true prevalence of MuKV in murine rodent populations in China.
最近，在中国的粪便样本中发现了一种新型家族成员鼠诺如病毒（MuKV）。由于关于 MuKV 在其他鼠科啮齿动物物种中传播的信息有限，我们促使我们调查其在中国的流行情况，并对其进行遗传特征分析。2015 年至 2017 年间，从中国南部三个地区的这三种鼠科啮齿动物中筛选了 243 份粪便样本，以检测 MuKV 的存在。总体患病率为 23.0％（56/243）。获得了三个完整的 MuKV 多蛋白序列，并确定了基因组组织。系统进化分析表明，我们的序列与中国株密切相关，属于属中的 。需要进一步研究以了解 MuKV 在我国鼠科啮齿动物种群中的真实流行情况。
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