Mukherjee B B, Mobry P M
J Gen Virol. 1979 Jun;43(3):723-8. doi: 10.1099/0022-1317-43-3-723.
Total RNAs from four BALB/c mouse tissues, containing mostly non-dividing cells (liver and kidney) or variable proportions of dividing cells (uterus and embryo) were analysed for sequences complementary to 3H-DNA transcripts synthesized from BALB/c endogenous. N- and X-tropic retroviruses. Extensive transcription of virogene information was detected in the tissues examined, but such transcription was found to be mostly limited to the homologous regions of the two virus genomes. No additivity of hybridization values could be detected when RNAs from two different tissues were mixed, which suggests that BALB/c mouse liver, kidney, uterus and embryo transcribe a common set of nucleic acid sequences of the homologous regions of the N- and X-tropic viral genomes, in addition to other sequences of the same region that are specific for indiviual tissues.
对来自四种BALB/c小鼠组织的总RNA进行了分析，这些组织大多含有非分裂细胞（肝脏和肾脏）或不同比例的分裂细胞（子宫和胚胎），以寻找与从BALB/c内源性N-嗜性和X-嗜性逆转录病毒合成的3H-DNA转录本互补的序列。在所检查的组织中检测到了病毒基因信息的广泛转录，但发现这种转录大多局限于两种病毒基因组的同源区域。当将来自两种不同组织的RNA混合时，未检测到杂交值的加和性，这表明BALB/c小鼠的肝脏、肾脏、子宫和胚胎除了转录同一区域中特定于单个组织的其他序列外，还转录N-嗜性和X-嗜性病毒基因组同源区域的一组共同核酸序列。
