Regitnig P, Nader A, Wiener H
Institut für Pathologie, Medizinische Universität Graz, Auenbruggerplatz 25, 8036, Graz, Österreich.
Pathologe. 2012 Jul;33(4):293-300. doi: 10.1007/s00292-012-1574-z.
The success of cytology in screening programs for cervical cancer is highly dependent on the smear quality. Interdisciplinary projects which evaluate the smear quality and the results of collection devices could be helpful for an improvement and a successful example for quality improvement is presented here. An average of 83% technically adequate and representative smears was documented for 12 million conventional PAP smears; however only an average of 68% technically adequate and representative smears was found for the group of least successful smear takers of all laboratories. This indicates a potential for improvement. Following an interdisciplinary project on smear quality improvement the average rate of representative smears increased from 69 to 83% and in another project this rate remained stable at 86%. Based on 158,411 conventional smears, representative smears were achieved in 92% using Cervex-Brush®, 86% using Szalay Spatula and 82% Cytobrush methods. The combinations of Cytobrush with the Ayre wooden spatula, cotton wool swab or Szalay Spatula achieved 97%, 94% and 92% representative smears, respectively.
细胞学在宫颈癌筛查项目中的成功高度依赖于涂片质量。评估涂片质量和采集设备结果的跨学科项目可能有助于改进，本文展示了一个质量改进的成功案例。在1200万份传统巴氏涂片中，平均有83%的涂片在技术上是足够的且具有代表性；然而，在所有实验室中涂片采集最不成功的一组中，平均只有68%的涂片在技术上是足够的且具有代表性。这表明存在改进的潜力。在一个关于涂片质量改进的跨学科项目之后，具有代表性涂片的平均比例从69%提高到了83%，在另一个项目中，这一比例稳定在86%。基于158411份传统涂片，使用Cervex-Brush®获得具有代表性涂片的比例为92%，使用Szalay刮勺为86%，使用细胞刷方法为82%。细胞刷与艾尔木制刮勺、棉拭子或Szalay刮勺组合分别获得具有代表性涂片的比例为97%、94%和92%。
