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绿茶补充剂对肥胖患者血清元素、总抗氧化剂、脂质和葡萄糖值的影响。

Effects of green tea supplementation on elements, total antioxidants, lipids, and glucose values in the serum of obese patients.

机构信息

Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Wojska Polskiego 31 Str, 60-624 Poznan, Poland.

出版信息

Biol Trace Elem Res. 2012 Dec;149(3):315-22. doi: 10.1007/s12011-012-9448-z. Epub 2012 May 15.

DOI:10.1007/s12011-012-9448-z
PMID:22581111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3501173/
Abstract

The consumption of green tea has been associated with cardiovascular and metabolic diseases. There have been some studies on the influence of green tea on the mineral status of obese subjects, but they have not yielded conclusive results. The aim of the present study is to examine the effects of green tea extract on the mineral, body mass, lipid profile, glucose, and antioxidant status of obese patients. A randomized, double-blind, placebo-controlled study was conducted. Forty-six obese patients were randomly assigned to receive either 379 mg of green tea extract, or a placebo, daily for 3 months. At baseline, and after 3 months of treatment, the anthropometric parameters, blood pressure, and total antioxidant status were assessed, as were the levels of plasma lipids, glucose, calcium, magnesium, iron, zinc, and copper. We found that 3 months of green tea extract supplementation resulted in decreases in body mass index, waist circumference, and levels of total cholesterol, low-density cholesterol, and triglyceride. Increases in total antioxidant level and in zinc concentration in serum were also observed. Glucose and iron levels were lower in the green tea extract group than in the control, although HDL-cholesterol and magnesium were higher in the green tea extract group than in the placebo group. At baseline, a positive correlation was found between calcium and body mass index, as was a negative correlation between copper and triglycerides. After 3 months, a positive correlation between iron and body mass index and between magnesium and HDL-cholesterol, as well as a negative correlation between magnesium and glucose, were observed. The present findings demonstrate that green tea influences the body's mineral status. Moreover, the results of this study confirm the beneficial effects of green tea extract supplementation on body mass index, lipid profile, and total antioxidant status in patients with obesity.

摘要

绿茶的消费与心血管和代谢性疾病有关。已有一些关于绿茶对肥胖受试者矿物质状况影响的研究,但尚未得出明确的结论。本研究旨在探讨绿茶提取物对肥胖患者矿物质、体重、血脂谱、血糖和抗氧化状态的影响。进行了一项随机、双盲、安慰剂对照研究。将 46 名肥胖患者随机分为两组,分别每天服用 379 毫克绿茶提取物或安慰剂,持续 3 个月。在基线和治疗 3 个月后,评估了人体测量参数、血压和总抗氧化状态,以及血浆脂质、血糖、钙、镁、铁、锌和铜的水平。我们发现,3 个月的绿茶提取物补充剂可降低体重指数、腰围和总胆固醇、低密度胆固醇和甘油三酯水平。总抗氧化水平和血清锌浓度也有所增加。与对照组相比,绿茶提取物组的血糖和铁水平较低,而高密度脂蛋白胆固醇和镁水平较高。在基线时,发现钙与体重指数呈正相关,而铜与甘油三酯呈负相关。3 个月后,观察到铁与体重指数和镁与高密度脂蛋白胆固醇之间呈正相关,以及镁与血糖之间呈负相关。本研究结果表明,绿茶会影响人体的矿物质状况。此外,本研究的结果证实了绿茶提取物补充剂对肥胖患者体重指数、血脂谱和总抗氧化状态的有益影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9da/3501173/ffdaf104d5b0/12011_2012_9448_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9da/3501173/3ce1b63495f2/12011_2012_9448_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9da/3501173/ffdaf104d5b0/12011_2012_9448_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9da/3501173/3ce1b63495f2/12011_2012_9448_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9da/3501173/ffdaf104d5b0/12011_2012_9448_Fig2_HTML.jpg

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