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Type III secretion in Yersinia: injectisome or not?

作者信息

Edgren Tomas, Forsberg Ake, Rosqvist Roland, Wolf-Watz Hans

机构信息

Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden-MIMS, Umeå Centre for Microbial Research-UCMR, Umeå University, Umeå, Sweden.

出版信息

PLoS Pathog. 2012;8(5):e1002669. doi: 10.1371/journal.ppat.1002669. Epub 2012 May 10.

DOI:10.1371/journal.ppat.1002669
PMID:22589714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3349746/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c60e/3349746/b5611a975727/ppat.1002669.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c60e/3349746/b5611a975727/ppat.1002669.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c60e/3349746/b5611a975727/ppat.1002669.g001.jpg

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Translocation of surface-localized effectors in type III secretion.III 型分泌系统中表面定位效应因子的易位。
Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1639-44. doi: 10.1073/pnas.1013888108. Epub 2011 Jan 10.
2
Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip.脱氧胆酸盐在诱导IpaB募集至Ⅲ型分泌装置针尖的过程中与福氏志贺菌的IpaD相互作用。
J Biol Chem. 2008 Jul 4;283(27):18646-54. doi: 10.1074/jbc.M802799200. Epub 2008 May 1.
3
Protein delivery into eukaryotic cells by type III secretion machines.
描绘III型分泌系统ATP酶YsaN的N端结构域中控制其不同寡聚化状态的特定区域。
Front Mol Biosci. 2022 Sep 8;9:967974. doi: 10.3389/fmolb.2022.967974. eCollection 2022.
4
The Regulatory Circuit Underlying Downregulation of a Type III Secretion System in by Transcription Factor OmpR.转录因子 OmpR 下调 III 型分泌系统的调控回路。
Int J Mol Sci. 2022 Apr 26;23(9):4758. doi: 10.3390/ijms23094758.
5
The T3SS of : Expression, Structure, Function, and Role in Vacuole Escape.的三型分泌系统：表达、结构、功能及在液泡逃逸中的作用
Microorganisms. 2020 Dec 5;8(12):1933. doi: 10.3390/microorganisms8121933.
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Staying out or Going in? The Interplay between Type 3 and Type 5 Secretion Systems in Adhesion and Invasion of Enterobacterial Pathogens.留置还是进入？III 型和 V 型分泌系统在肠杆菌病原体黏附和侵袭中的相互作用。
Int J Mol Sci. 2020 Jun 8;21(11):4102. doi: 10.3390/ijms21114102.
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Identification of specific sequence motif of YopN of Yersinia pseudotuberculosis required for systemic infection.鉴定鼠疫假单胞菌 YopN 系统感染所需的特定序列基序。
Virulence. 2019 Dec;10(1):10-25. doi: 10.1080/21505594.2018.1551709.
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Discovering RNA-Based Regulatory Systems for Virulence.发现基于 RNA 的毒力调控系统。
Front Cell Infect Microbiol. 2018 Oct 25;8:378. doi: 10.3389/fcimb.2018.00378. eCollection 2018.
9
Bacterial type III secretion systems: a complex device for the delivery of bacterial effector proteins into eukaryotic host cells.细菌III型分泌系统：一种将细菌效应蛋白递送至真核宿主细胞的复杂装置。
FEMS Microbiol Lett. 2018 Oct 1;365(19). doi: 10.1093/femsle/fny201.
10
Gain-of-Function Analysis Reveals Important Virulence Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA.功能获得分析揭示了鼠疫耶尔森氏菌 III 型分泌系统效应物 YopJ、YopT 和 YpkA 的重要毒力作用。
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通过III型分泌机制将蛋白质递送至真核细胞。
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The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needles.耶尔森菌的V抗原在注射体针的尖端形成独特的结构。
Science. 2005 Oct 28;310(5748):674-6. doi: 10.1126/science.1118476.
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The role of multiplication of Pasteurella pestis in mononuclear phagocytes in the pathogenesis of flea-borne plague.鼠疫耶尔森菌在单核吞噬细胞中的增殖在蚤传鼠疫发病机制中的作用。
J Immunol. 1959 Oct;83:348-63.
6
Supramolecular structure of the Salmonella typhimurium type III protein secretion system.鼠伤寒沙门氏菌III型蛋白分泌系统的超分子结构
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EMBO J. 1996 Nov 1;15(21):5812-23.
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EMBO J. 1996 Oct 1;15(19):5191-201.
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Modulation of virulence factor expression by pathogen target cell contact.病原体与靶细胞接触对毒力因子表达的调控。
Science. 1996 Aug 30;273(5279):1231-3. doi: 10.1126/science.273.5279.1231.
10
The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells.弗氏志贺菌分泌的Ipa复合物促进其进入哺乳动物细胞。
Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1254-8. doi: 10.1073/pnas.93.3.1254.