Deng Ming Y, Millien Max, Jacques-Simon Rodney, Flanagan J Keith, Bracht Alexa J, Carrillo Consuelo, Barrette Roger W, Fabian Andrew, Mohamed Fawzi, Moran Karen, Rowland Jessica, Swenson Sabrina L, Jenkins-Moore Melinda, Koster Leo, Thomsen Bruce V, Mayr Gregory, Pyburn Dave, Morales Paula, Shaw John, Burrage Thomas, White William, McIntosh Michael T, Metwally Samia
U.S. Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, National Veterinary Services Laboratories, Foreign Animal Disease Diagnostic Laboratory, Greenport, NY 11944, USA.
J Vet Diagn Invest. 2012 Jul;24(4):671-8. doi: 10.1177/1040638712445769. Epub 2012 May 17.
In February and March 2009, approximately 1,500 backyard pigs of variable age became sick, and approximately 700 of them died or were euthanized in the Lower Artibonite Valley and the Lower Plateau of the Republic of Haiti. The main clinical sign was posterior ataxia followed by paresis and/or paralysis on the second or third day of illness. No gross lesions were observed at postmortem examinations. The morbidity and mortality were approximately 60% and 40%, respectively. Diagnostic samples (whole blood, brain, tonsil, lymph nodes, spleen, and lung) were negative for Classical swine fever virus and African swine fever virus. Porcine teschovirus type 1 was detected by reverse transcription polymerase chain reactions in brain samples. Results of virus isolation, electron microscopy of virus particles, histopathological analysis on brain tissues, nucleic acid sequencing, and phylogenetic analysis of the viral isolate supported the diagnosis of teschovirus encephalomyelitis. The outbreak of the disease in Haiti is the first appearance of the severe form of teschovirus encephalomyelitis in the Americas. This disease poses a potential threat to the swine industries in other Caribbean countries, as well as to Central and North American countries.
2009年2月和3月，海地共和国下阿蒂博尼特山谷和下高原地区约1500头不同年龄段的家猪患病，其中约700头死亡或被安乐死。主要临床症状为后躯共济失调，随后在发病第二天或第三天出现轻瘫和/或瘫痪。尸检未观察到明显病变。发病率和死亡率分别约为60%和40%。诊断样本（全血、脑、扁桃体、淋巴结、脾脏和肺）经检测，猪瘟病毒和非洲猪瘟病毒均为阴性。通过逆转录聚合酶链反应在脑样本中检测到1型猪捷申病毒。病毒分离、病毒颗粒电子显微镜检查、脑组织组织病理学分析、核酸测序以及病毒分离株的系统发育分析结果均支持捷申病毒脑脊髓炎的诊断。海地此次疾病暴发是美洲首次出现严重形式的捷申病毒脑脊髓炎。这种疾病对其他加勒比国家以及中美洲和北美洲国家的养猪业构成潜在威胁。
