Institute for Advanced Biomedical Technologies, G. D'Annunzio University Foundation, G. D'Annunzio University, 66100 Chieti, Italy.
Neuron. 2012 May 24;74(4):753-64. doi: 10.1016/j.neuron.2012.03.031.
We used magneto-encephalography to study the temporal dynamics of band-limited power correlation at rest within and across six brain networks previously defined by prior functional magnetic resonance imaging (fMRI) studies. Epochs of transiently high within-network band limited power (BLP) correlation were identified and correlation of BLP time-series across networks was assessed in these epochs. These analyses demonstrate that functional networks are not equivalent with respect to cross-network interactions. The default-mode network and the posterior cingulate cortex, in particular, exhibit the highest degree of transient BLP correlation with other networks especially in the 14-25 Hz (β band) frequency range. Our results indicate that the previously demonstrated neuroanatomical centrality of the PCC and DMN has a physiological counterpart in the temporal dynamics of network interaction at behaviorally relevant timescales. This interaction involved subsets of nodes from other networks during periods in which their internal correlation was low.
我们使用脑磁图研究了在静息状态下，六个先前通过功能磁共振成像（fMRI）研究定义的大脑网络内和跨网络的带限功率相关性的时间动态。识别了网络内瞬时高带限功率（BLP）相关性的时段，并评估了这些时段内网络间 BLP 时间序列的相关性。这些分析表明，功能网络在跨网络相互作用方面并不等同。特别是默认模式网络和后扣带皮层在 14-25 Hz（β 频段）频率范围内与其他网络表现出最高程度的瞬态 BLP 相关性。我们的结果表明，先前证明的后扣带皮层和默认模式网络的神经解剖学中心性在行为相关时间尺度上的网络相互作用的时间动态中具有生理对应物。这种相互作用涉及其他网络的节点子集，而这些节点子集的内部相关性较低。
