Department of Molecular Biology, Max Planck Institute for Developmental Biology Tübingen, Germany.
Front Plant Sci. 2011 Nov 4;2:70. doi: 10.3389/fpls.2011.00070. eCollection 2011.
Beyond their metabolic roles, sugars can also act as messengers in signal transduction. Trehalose, a sugar found in many species of plants and animals, is a non-reducing disaccharide composed of two glucose moieties. Its synthesis in plants is a two-step process, involving the production of trehalose-6-phosphate (T6P) catalyzed by trehalose-6-phosphate synthase (TPS) and its consecutive dephosphorylation to trehalose, catalyzed by trehalose-6-phosphate phosphatase (TPP). T6P has recently emerged as an important signaling metabolite, regulating carbon assimilation and sugar status in plants. In addition, T6P has also been demonstrated to play an essential role in plant development. This review recapitulates the recent advances we have made in understanding the role of T6P in coordinating diverse metabolic and developmental processes.
除了代谢作用外，糖还可以作为信号转导中的信使。海藻糖是一种在许多动植物物种中发现的非还原二糖，由两个葡萄糖单元组成。它在植物中的合成是一个两步过程，涉及海藻糖-6-磷酸（T6P）的合成，由海藻糖-6-磷酸合酶（TPS）催化，然后连续磷酸化生成海藻糖，由海藻糖-6-磷酸磷酸酶（TPP）催化。T6P 最近作为一种重要的信号代谢物出现，调节植物中的碳同化和糖状态。此外，T6P 也被证明在植物发育中起着重要作用。本综述总结了我们在理解 T6P 在协调多种代谢和发育过程中的作用方面取得的最新进展。
