Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, New York 13699, United States.
Anal Chem. 2012 Jul 3;84(13):5463-9. doi: 10.1021/ac3007076. Epub 2012 Jun 8.
Novel biosensors based on the biocomputing concept digitally process multiple biochemical signals through Boolean logic networks of coupled biomolecular reactions and produce output in the form of a YES/NO response. Compared to traditional single-analyte sensing devices, biocomputing approach enables a high-fidelity multianalyte biosensing, particularly beneficial for biomedical applications.
基于生物计算概念的新型生物传感器通过耦合生物分子反应的布尔逻辑网络对多个生化信号进行数字处理，并以 YES/NO 响应的形式产生输出。与传统的单分析物传感设备相比，生物计算方法能够实现高保真度的多分析物生物传感，特别有益于生物医学应用。
