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外阴阴道念珠菌病患者宫颈阴道分泌物中针对白色念珠菌细胞壁抗原的不同抗体反应。

Different antibody response against Candida albicans cell wall antigens in cervicovaginal secretions of patients with vulvovaginal candidiasis.

作者信息

Schneider J, Vicandi J, Regulez P, Quindós G, Pontón J, Cisterna R

机构信息

Departamento de Obstetricia y Ginecología, Facultad de Medicina y Odontología, Universidad del País Vasco, Bilbao, España.

出版信息

Gynecol Obstet Invest. 1990;30(3):174-7. doi: 10.1159/000293258.

DOI:10.1159/000293258
PMID:2265804
Abstract

Vaginal washings from 118 women were investigated by means of immunofluorescence for the presence of antibodies against Candida albicans. A significantly (p less than 0.02) higher antibody titer was found in the samples from patients with clinically evident vulvovaginal candidiasis. Vaginal secretions from those patients with a positive culture for C. albicans were assayed by means of Western blotting. A distinct band pattern was found in the group of patients with a positive culture and the classical clinical picture of C. albicans vulvovaginitis.

摘要

采用免疫荧光法对118名女性的阴道冲洗液进行检测,以确定是否存在抗白色念珠菌的抗体。在临床诊断为外阴阴道念珠菌病的患者样本中,抗体滴度显著升高(p<0.02)。对白色念珠菌培养呈阳性的患者的阴道分泌物进行蛋白质印迹分析。在白色念珠菌外阴阴道炎培养呈阳性且具有典型临床症状的患者组中发现了独特的条带模式。

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Different antibody response against Candida albicans cell wall antigens in cervicovaginal secretions of patients with vulvovaginal candidiasis.外阴阴道念珠菌病患者宫颈阴道分泌物中针对白色念珠菌细胞壁抗原的不同抗体反应。
Gynecol Obstet Invest. 1990;30(3):174-7. doi: 10.1159/000293258.
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[IgA, IgE and IgG subclasses to Candida albicans in serum and vaginal fluid from patients with vulvovaginal candidiasis].[外阴阴道念珠菌病患者血清和阴道分泌物中针对白色念珠菌的IgA、IgE和IgG亚类]
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引用本文的文献

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Candida albicans stress mannoproteins expression in superficial and systemic candidiasis. Stress mannoproteins in Candida albicans.白色念珠菌应激甘露糖蛋白在浅表和全身性念珠菌病中的表达。白色念珠菌中的应激甘露糖蛋白。
Mycopathologia. 1996;133(2):89-94. doi: 10.1007/BF00439119.
2
Production and function of cytokines in natural and acquired immunity to Candida albicans infection.白色念珠菌感染天然免疫和获得性免疫中细胞因子的产生与功能
Microbiol Rev. 1995 Dec;59(4):646-72. doi: 10.1128/mr.59.4.646-672.1995.