Department of Endocrinology, Adana Numune Education and Training Hospital, Turkey.
Endocr J. 2012;59(8):705-8. doi: 10.1507/endocrj.ej12-0035. Epub 2012 May 12.
Depression and chronic autoimmune thyroiditis are common diseases. The aim of this study was to determine whether the frequency of depression is elevated in patients with chronic autoimmune thyroiditis and normal thyroid function. A total of 201 subjects were included, of whom 107 and 94 participants were healthy or had euthyroid chronic autoimmune thyroiditis, respectively. Serum thyroid hormone levels and thyroid auto-antibodies were measured in all subjects. All participants were evaluated with Hamilton Depression Rating Scale (HDRS). HDRS scores of patients with euthyroid chronic autoimmune thyroiditis were higher than in healthy participants. This study suggests a possible association between depression and chronic autoimmune thyroiditis. The depression risk may be increased in patients with chronic autoimmune thyroiditis and normal thyroid function.
抑郁症和慢性自身免疫性甲状腺炎是常见疾病。本研究旨在确定甲状腺功能正常的慢性自身免疫性甲状腺炎患者中抑郁症的发病率是否升高。共纳入 201 名受试者，其中 107 名健康受试者和 94 名甲状腺功能正常的慢性自身免疫性甲状腺炎患者。所有受试者均检测血清甲状腺激素水平和甲状腺自身抗体。所有参与者均进行汉密尔顿抑郁量表（HDRS）评估。甲状腺功能正常的慢性自身免疫性甲状腺炎患者的 HDRS 评分高于健康参与者。本研究提示抑郁症与慢性自身免疫性甲状腺炎之间可能存在关联。甲状腺功能正常的慢性自身免疫性甲状腺炎患者的抑郁风险可能增加。
