Bartlett Sarah, Cai Andrew, Cairns Hugh
Renal Medicine, Kings College Hospital NHS Foundation Trust, Denmark Hill, London, United Kingdom.
BMJ Case Rep. 2011 Jul 15;2011:bcr0420114072. doi: 10.1136/bcr.04.2011.4072.
The authors present an interesting case of non-arteritic anterior ischaemic optic neuropathy (NAION) after 2 h of haemodialysis, in a 42-year-old Caucasian woman with anaemia (haemoglobin 7.1 g/dl) uraemia (56.3 mmol/l), spurious hypotension (42/26 mm Hg) and previous history of anterior ischaemic optic neuropathy (AION) in the other eye. Thirteen cases of haemodialysis related NAION in adults have been reported to date. NAION is produced when oxygen delivery to the optic nerve is compromised resulting in hypoxic swelling, nerve compression in the optic canal and ischaemia of the optic nerve head. It typically presents as a sudden, unilateral and painless inferior visual field defect with a fixed unreactive pupil after a period of relative hypotension. Clinicians should be aware of this unusual complication when considering and explaining dialysis options, particularly in patients with other risk factors such as hypotension, anaemia, significant uraemia and previous history of AION.
作者报告了一例有趣的病例,一名42岁的患有贫血(血红蛋白7.1g/dl)、尿毒症(56.3mmol/l)、假性低血压(42/26mmHg)且另一只眼有前部缺血性视神经病变(AION)病史的白种女性,在血液透析2小时后发生了非动脉炎性前部缺血性视神经病变(NAION)。迄今为止,已报告了13例成人血液透析相关的NAION病例。当视神经的氧气供应受到损害,导致缺氧性肿胀、视神经管内神经受压以及视神经乳头缺血时,就会产生NAION。它通常表现为在一段相对低血压期后,突然出现的单侧、无痛性下视野缺损以及固定的无反应瞳孔。在考虑和解释透析方案时,临床医生应意识到这种不寻常的并发症尤其在伴有其他危险因素(如低血压、贫血、严重尿毒症和AION病史)的患者中。