Belchior Inês, Seabra Bárbara, Duarte Raquel
Department of Pulmonology, Hospital de São João, Porto, Portugal.
BMJ Case Rep. 2011 Jun 15;2011:bcr1120103496. doi: 10.1136/bcr.11.2010.3496.
A 42-year-old female laboratory worker presented with a left index finger skin lesion after an accidental prick while handling samples of a cultural exam of Mycobacterium tuberculosis. Surgical excision was performed and pathology analysis revealed a dermic chronic inflammatory process with no granulomas. Later, a non-painful lymphadenopathy appeared in the left axilla as well as brownish indurated skin lesions in the lower limbs consistent with erythema nodosum. Fine needle aspiration biopsy of the lymph node revealed epithelioid granulomas, Langhans' multinucleated giant cells and the presence of acid-fast bacilli. Standard tuberculosis treatment resulted in regression of lesions and no relapses occurred in the 2-year follow-up period.
一名42岁的女性实验室工作人员在处理结核分枝杆菌培养检查样本时意外被刺伤，之后左手食指出现皮肤损伤。进行了手术切除，病理分析显示为真皮慢性炎症过程，无肉芽肿形成。后来，左腋窝出现无痛性淋巴结病，下肢出现与结节性红斑一致的褐色硬结性皮肤损伤。对淋巴结进行细针穿刺活检，发现上皮样肉芽肿、朗汉斯多核巨细胞以及抗酸杆菌。标准的抗结核治疗使病变消退，在2年的随访期内未出现复发。
