Department of Radiology, Oncology and Radiation Science, Section of Radiology, Akademiska sjukhuset, Uppsala University, Uppsala, Sweden,
Insights Imaging. 2012 Aug;3(4):387-93. doi: 10.1007/s13244-012-0166-z. Epub 2012 May 3.
The purpose of this study was to test the stereology method using several grid sizes for measuring liver volume and to find which grid provides an accurate estimate of liver volume.
Liver volume was measured by volumetry in 41 sets of liver MRI. MRI was performed before and after different weight-reducing regimens. Grids of 3, 4, 5, and 6 cm were used to measure liver volume on different occasions by stereology. The liver volume and the changes in volume before and after treatment were compared between stereology and volumetry.
There was no significant difference in measurements between stereology methods and volumetry (p > 0.05). The mean differences in liver volume between stereology based on 3-, 4-, 5-, and 6-cm grids and volumetry were 37, 3, 132, and 23 mL, respectively, and the differences in measurement of liver volume change were 21, 2, 19, and 76 mL, respectively. The mean time required for measurement by stereology was 59-190 s.
Stereology employing 3- and 4-cm grids can rapidly provide accurate results for measuring liver volume and changes in liver volume.
• Statistical methods can be used for measuring area/volume in radiology. • Measuring liver volume by stereology by 4-cm grids can be done in less than two minutes. • Follow-up of liver volume is highly accurate with stereological methods.
本研究旨在测试使用不同网格大小测量肝体积的体视学法，并寻找提供肝体积准确估计的网格。
通过 41 组肝 MRI 进行体积测量来测量肝体积。MRI 在不同减重方案前后进行。使用体视学法在不同时间点使用 3、4、5 和 6cm 的网格来测量肝体积。比较体视学法和体积测量法测量的肝体积和治疗前后的体积变化。
体视学法与体积测量法之间的测量无显著差异（p>0.05）。基于 3、4、5 和 6cm 网格的体视学法和体积测量法测量的肝体积平均差异分别为 37、3、132 和 23mL，测量的肝体积变化差异分别为 21、2、19 和 76mL。体视学法测量所需的平均时间为 59-190s。
使用 3 和 4cm 网格的体视学法可以快速提供肝体积和肝体积变化的准确结果。
统计学方法可用于测量放射学中的面积/体积。
通过 4cm 网格进行体视学法测量肝体积可在两分钟内完成。
体视学法对肝体积的随访高度准确。
