Hansen E S
Institute of Community Health, University of Odense, Denmark.
Br J Ind Med. 1990 Dec;47(12):805-9. doi: 10.1136/oem.47.12.805.
This study was set up to investigate the effect of exposure to combustion effluents on the chronic health of firefighters. A cohort of firefighters was followed up through 10 years with regard to cause specific mortality. Comparisons were made with another cohort of civil servants and salaried employees in physically demanding jobs. After a latency of five years, an excess mortality from cancer was seen for persons aged 30 to 74 (standardised mortality ratio (SMR) 173, 95% confidence interval (95% CI) 104-270). A significant increase in lung cancer was seen in the group aged 60 to 74 (SMR 317, 95% CI 117-691), whereas non-pulmonary cancer was significantly increased in the group aged 30 to 49 (SMR 575, 95% CI 187-1341). It is concluded that inhalation of carcinogenic and toxic compounds during firefighting may constitute an occupational cancer risk. An extended use of respiratory protective equipment is advocated.
本研究旨在调查接触燃烧废气对消防员慢性健康的影响。对一组消防员进行了为期10年的特定病因死亡率随访。并与另一组从事体力要求较高工作的公务员和受薪雇员进行了比较。经过5年的潜伏期后,30至74岁人群的癌症死亡率出现超额(标准化死亡率比(SMR)为173,95%置信区间(95%CI)为104 - 270)。60至74岁组的肺癌死亡率显著增加(SMR为317,95%CI为117 - 691),而30至49岁组的非肺癌癌症死亡率显著增加(SMR为575,95%CI为187 - 1341)。得出的结论是,灭火过程中吸入致癌和有毒化合物可能构成职业癌症风险。提倡广泛使用呼吸防护设备。