人冠状病毒 NL63 在中国重庆住院呼吸道感染患儿中的研究：一项为期 2 年的研究。
Human coronavirus NL63 in hospitalized children with respiratory infection: a 2-year study from Chongqing, China.
机构信息
Division of Nephrology and Immunology, Childrens Hospital of Chongqing Medical University, Chongqing, China.
出版信息
Indian Pediatr. 2012 Oct;49(10):825-8. doi: 10.1007/s13312-012-0194-1. Epub 2012 Jun 10.
Abstract
Human coronavirus (HCoV) NL63, a newly discovered coronavirus, has been associated with acute lower respiratory tract infections (ALRTI). We detected HCoV-NL63 via reverse transcriptional PCR (RT-PCR) in eight out of 878 respiratory specimens freshly collected from hospitalized children with ALRTI between April 2006 and March 2008 in Childrens Hospital of Chongqing Medical University. Peak of HCoV-NL63 activity often appeared during the summer and autumn in Chongqing area. All children with HCoV-NL63 infection were <1 year of age. The diagnosis included bronchial pneumonia, bronchitis, interstitial pneumonia and bronchiolitis. All children recovered.
摘要
人冠状病毒（HCoV）NL63 是一种新发现的冠状病毒，与急性下呼吸道感染（ALRTI）有关。我们通过逆转录 PCR（RT-PCR）在重庆医科大学儿童医院 2006 年 4 月至 2008 年 3 月期间采集的 878 份急性下呼吸道感染住院患儿的呼吸道标本中检测到 8 份 HCoV-NL63。重庆地区 HCoV-NL63 的活动高峰期通常出现在夏季和秋季。所有 HCoV-NL63 感染患儿均<1 岁。诊断包括支气管肺炎、支气管炎、间质性肺炎和细支气管炎。所有患儿均痊愈。
相似文献
1
Human coronavirus NL63 in hospitalized children with respiratory infection: a 2-year study from Chongqing, China.人冠状病毒 NL63 在中国重庆住院呼吸道感染患儿中的研究：一项为期 2 年的研究。
Indian Pediatr. 2012 Oct;49(10):825-8. doi: 10.1007/s13312-012-0194-1. Epub 2012 Jun 10.
2
[The detection and clinical feature of HcoV-nL63 in children with acute respiratory tract infection in Lanzhou city].[兰州市急性呼吸道感染儿童中HcoV-nL63的检测及临床特征]
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2012 Dec;26(6):409-11.
3
Epidemiology and clinical characteristics of human coronaviruses OC43, 229E, NL63, and HKU1: a study of hospitalized children with acute respiratory tract infection in Guangzhou, China.人冠状病毒 OC43、229E、NL63 和 HKU1 的流行病学和临床特征：中国广州急性呼吸道感染住院儿童的研究。
Eur J Clin Microbiol Infect Dis. 2018 Feb;37(2):363-369. doi: 10.1007/s10096-017-3144-z. Epub 2017 Dec 6.
4
Human Coronavirus-NL63 infections in Korean children, 2004-2006.2004 - 2006年韩国儿童中的人冠状病毒NL63感染情况
J Clin Virol. 2007 Jan;38(1):27-31. doi: 10.1016/j.jcv.2006.10.009. Epub 2006 Nov 29.
5
The dominance of human coronavirus OC43 and NL63 infections in infants.人冠状病毒 OC43 和 NL63 感染在婴儿中的优势。
J Clin Virol. 2012 Feb;53(2):135-9. doi: 10.1016/j.jcv.2011.11.011. Epub 2011 Dec 19.
6
Human coronavirus NL63: a clinically important virus?人冠状病毒 NL63：一种具有临床重要性的病毒？
Future Microbiol. 2011 Feb;6(2):153-9. doi: 10.2217/fmb.10.166.
7
Discovery of a subgenotype of human coronavirus NL63 associated with severe lower respiratory tract infection in China, 2018.中国 2018 年发现与严重下呼吸道感染相关的人冠状病毒 NL63 的一个亚基因型。
Emerg Microbes Infect. 2020 Jan 29;9(1):246-255. doi: 10.1080/22221751.2020.1717999. eCollection 2020.
8
Epidemiology and clinical presentations of human coronavirus NL63 infections in hong kong children.香港儿童中人类冠状病毒 NL63 感染的流行病学和临床特征。
J Clin Microbiol. 2009 Nov;47(11):3486-92. doi: 10.1128/JCM.00832-09. Epub 2009 Sep 16.
9
Epidemiology of human coronavirus NL63 infection among hospitalized patients with pneumonia in Taiwan.台湾地区住院肺炎患者中人类冠状病毒 NL63 感染的流行病学研究。
J Microbiol Immunol Infect. 2017 Dec;50(6):763-770. doi: 10.1016/j.jmii.2015.10.008. Epub 2015 Nov 19.
10
[Prevalence and clinical characteristics of coronavirus NL63 infection in children hospitalized for acute lower respiratory tract infections in Changsha].[长沙急性下呼吸道感染住院儿童中冠状病毒NL63感染的患病率及临床特征]
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2012 Apr;26(2):133-5.
引用本文的文献
1
Global Seasonality of Human Coronaviruses: A Systematic Review.人类冠状病毒的全球季节性：一项系统综述
Open Forum Infect Dis. 2020 Oct 18;7(11):ofaa443. doi: 10.1093/ofid/ofaa443. eCollection 2020 Nov.
2
3
A Single-Center Study of Viral Respiratory Tract Infections in Hospitalized Children From the Kurdistan Region of Iraq.伊拉克库尔德地区住院儿童病毒性呼吸道感染的单中心研究
Glob Pediatr Health. 2018 Jul 10;5:2333794X18784996. doi: 10.1177/2333794X18784996. eCollection 2018.
4
Epidemiology of human coronavirus NL63 infection among hospitalized patients with pneumonia in Taiwan.台湾地区住院肺炎患者中人类冠状病毒 NL63 感染的流行病学研究。
J Microbiol Immunol Infect. 2017 Dec;50(6):763-770. doi: 10.1016/j.jmii.2015.10.008. Epub 2015 Nov 19.
本文引用的文献
1
Epidemiology and clinical presentations of human coronavirus NL63 infections in hong kong children.香港儿童中人类冠状病毒 NL63 感染的流行病学和临床特征。
J Clin Microbiol. 2009 Nov;47(11):3486-92. doi: 10.1128/JCM.00832-09. Epub 2009 Sep 16.
2
Human coronavirus NL63 associated with lower respiratory tract symptoms in early life.人冠状病毒NL63与早期下呼吸道症状有关。
Pediatr Infect Dis J. 2005 Nov;24(11):1015-7. doi: 10.1097/01.inf.0000183773.80217.12.
3
Human coronavirus NL-63 infections in children: a 1-year study.儿童人冠状病毒NL-63感染：一项为期一年的研究。
J Clin Microbiol. 2005 Sep;43(9):4567-73. doi: 10.1128/JCM.43.9.4567-4573.2005.
4
Croup is associated with the novel coronavirus NL63.哮吼与新型冠状病毒NL63有关。
PLoS Med. 2005 Aug;2(8):e240. doi: 10.1371/journal.pmed.0020240. Epub 2005 Aug 23.
5
Human coronavirus NL63, France.人冠状病毒NL63，法国。
Emerg Infect Dis. 2005 Aug;11(8):1225-9. doi: 10.3201/eid1108.050110.
6
Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China.中国香港地区因急性呼吸道疾病住院儿童的人冠状病毒NL63感染及其他冠状病毒感染情况。
Clin Infect Dis. 2005 Jun 15;40(12):1721-9. doi: 10.1086/430301. Epub 2005 May 10.
7
A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium.一种新型全冠状病毒逆转录聚合酶链反应检测方法：在比利时因呼吸道感染住院的儿童中频繁检测到人类冠状病毒NL63 。
BMC Infect Dis. 2005 Feb 1;5:6. doi: 10.1186/1471-2334-5-6.
8
Human coronavirus NL63 infection in Canada.加拿大的人冠状病毒NL63感染。
J Infect Dis. 2005 Feb 15;191(4):503-6. doi: 10.1086/426869. Epub 2005 Jan 4.
9
Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children.一种与婴幼儿呼吸道疾病相关的新型人类冠状病毒的证据。
J Infect Dis. 2005 Feb 15;191(4):492-8. doi: 10.1086/428138. Epub 2005 Jan 14.
10
New human coronavirus, HCoV-NL63, associated with severe lower respiratory tract disease in Australia.新型人类冠状病毒HCoV-NL63与澳大利亚严重下呼吸道疾病相关。
J Med Virol. 2005 Mar;75(3):455-62. doi: 10.1002/jmv.20288.
Zotero 插件