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Human coronavirus NL63 in hospitalized children with respiratory infection: a 2-year study from Chongqing, China.人冠状病毒 NL63 在中国重庆住院呼吸道感染患儿中的研究:一项为期 2 年的研究。
Indian Pediatr. 2012 Oct;49(10):825-8. doi: 10.1007/s13312-012-0194-1. Epub 2012 Jun 10.
2
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J Clin Virol. 2012 Feb;53(2):135-9. doi: 10.1016/j.jcv.2011.11.011. Epub 2011 Dec 19.
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Discovery of a subgenotype of human coronavirus NL63 associated with severe lower respiratory tract infection in China, 2018.中国 2018 年发现与严重下呼吸道感染相关的人冠状病毒 NL63 的一个亚基因型。
Emerg Microbes Infect. 2020 Jan 29;9(1):246-255. doi: 10.1080/22221751.2020.1717999. eCollection 2020.
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Epidemiology and clinical presentations of human coronavirus NL63 infections in hong kong children.香港儿童中人类冠状病毒 NL63 感染的流行病学和临床特征。
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Epidemiology of human coronavirus NL63 infection among hospitalized patients with pneumonia in Taiwan.台湾地区住院肺炎患者中人类冠状病毒 NL63 感染的流行病学研究。
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Survey of WU and KI polyomaviruses, coronaviruses, respiratory syncytial virus and parechovirus in children under 5 years of age in Tehran, Iran.伊朗德黑兰5岁以下儿童中WU和KI多瘤病毒、冠状病毒、呼吸道合胞病毒和细小病毒的调查
Iran J Microbiol. 2020 Apr;12(2):164-169.
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A Single-Center Study of Viral Respiratory Tract Infections in Hospitalized Children From the Kurdistan Region of Iraq.伊拉克库尔德地区住院儿童病毒性呼吸道感染的单中心研究
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Epidemiology of human coronavirus NL63 infection among hospitalized patients with pneumonia in Taiwan.台湾地区住院肺炎患者中人类冠状病毒 NL63 感染的流行病学研究。
J Microbiol Immunol Infect. 2017 Dec;50(6):763-770. doi: 10.1016/j.jmii.2015.10.008. Epub 2015 Nov 19.

本文引用的文献

1
Epidemiology and clinical presentations of human coronavirus NL63 infections in hong kong children.香港儿童中人类冠状病毒 NL63 感染的流行病学和临床特征。
J Clin Microbiol. 2009 Nov;47(11):3486-92. doi: 10.1128/JCM.00832-09. Epub 2009 Sep 16.
2
Human coronavirus NL63 associated with lower respiratory tract symptoms in early life.人冠状病毒NL63与早期下呼吸道症状有关。
Pediatr Infect Dis J. 2005 Nov;24(11):1015-7. doi: 10.1097/01.inf.0000183773.80217.12.
3
Human coronavirus NL-63 infections in children: a 1-year study.儿童人冠状病毒NL-63感染:一项为期一年的研究。
J Clin Microbiol. 2005 Sep;43(9):4567-73. doi: 10.1128/JCM.43.9.4567-4573.2005.
4
Croup is associated with the novel coronavirus NL63.哮吼与新型冠状病毒NL63有关。
PLoS Med. 2005 Aug;2(8):e240. doi: 10.1371/journal.pmed.0020240. Epub 2005 Aug 23.
5
Human coronavirus NL63, France.人冠状病毒NL63,法国。
Emerg Infect Dis. 2005 Aug;11(8):1225-9. doi: 10.3201/eid1108.050110.
6
Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China.中国香港地区因急性呼吸道疾病住院儿童的人冠状病毒NL63感染及其他冠状病毒感染情况。
Clin Infect Dis. 2005 Jun 15;40(12):1721-9. doi: 10.1086/430301. Epub 2005 May 10.
7
A novel pancoronavirus RT-PCR assay: frequent detection of human coronavirus NL63 in children hospitalized with respiratory tract infections in Belgium.一种新型全冠状病毒逆转录聚合酶链反应检测方法:在比利时因呼吸道感染住院的儿童中频繁检测到人类冠状病毒NL63 。
BMC Infect Dis. 2005 Feb 1;5:6. doi: 10.1186/1471-2334-5-6.
8
Human coronavirus NL63 infection in Canada.加拿大的人冠状病毒NL63感染。
J Infect Dis. 2005 Feb 15;191(4):503-6. doi: 10.1086/426869. Epub 2005 Jan 4.
9
Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children.一种与婴幼儿呼吸道疾病相关的新型人类冠状病毒的证据。
J Infect Dis. 2005 Feb 15;191(4):492-8. doi: 10.1086/428138. Epub 2005 Jan 14.
10
New human coronavirus, HCoV-NL63, associated with severe lower respiratory tract disease in Australia.新型人类冠状病毒HCoV-NL63与澳大利亚严重下呼吸道疾病相关。
J Med Virol. 2005 Mar;75(3):455-62. doi: 10.1002/jmv.20288.

人冠状病毒 NL63 在中国重庆住院呼吸道感染患儿中的研究:一项为期 2 年的研究。

Human coronavirus NL63 in hospitalized children with respiratory infection: a 2-year study from Chongqing, China.

机构信息

Division of Nephrology and Immunology, Childrens Hospital of Chongqing Medical University, Chongqing, China.

出版信息

Indian Pediatr. 2012 Oct;49(10):825-8. doi: 10.1007/s13312-012-0194-1. Epub 2012 Jun 10.

DOI:10.1007/s13312-012-0194-1
PMID:22728623
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7096939/
Abstract

Human coronavirus (HCoV) NL63, a newly discovered coronavirus, has been associated with acute lower respiratory tract infections (ALRTI). We detected HCoV-NL63 via reverse transcriptional PCR (RT-PCR) in eight out of 878 respiratory specimens freshly collected from hospitalized children with ALRTI between April 2006 and March 2008 in Childrens Hospital of Chongqing Medical University. Peak of HCoV-NL63 activity often appeared during the summer and autumn in Chongqing area. All children with HCoV-NL63 infection were <1 year of age. The diagnosis included bronchial pneumonia, bronchitis, interstitial pneumonia and bronchiolitis. All children recovered.

摘要

人冠状病毒(HCoV)NL63 是一种新发现的冠状病毒,与急性下呼吸道感染(ALRTI)有关。我们通过逆转录 PCR(RT-PCR)在重庆医科大学儿童医院 2006 年 4 月至 2008 年 3 月期间采集的 878 份急性下呼吸道感染住院患儿的呼吸道标本中检测到 8 份 HCoV-NL63。重庆地区 HCoV-NL63 的活动高峰期通常出现在夏季和秋季。所有 HCoV-NL63 感染患儿均<1 岁。诊断包括支气管肺炎、支气管炎、间质性肺炎和细支气管炎。所有患儿均痊愈。