Division of Plant Sciences, University of Dundee at the James Hutton Institute, Invergowrie, Dundee DD2 5DA, Scotland, UK.
Trends Plant Sci. 2012 Oct;17(10):616-23. doi: 10.1016/j.tplants.2012.06.001. Epub 2012 Jun 27.
More than 60% of intron-containing genes undergo alternative splicing (AS) in plants. This number will increase when AS in different tissues, developmental stages, and environmental conditions are explored. Although the functional impact of AS on protein complexity is still understudied in plants, recent examples demonstrate its importance in regulating plant processes. AS also regulates transcript levels and the link with nonsense-mediated decay and generation of unproductive mRNAs illustrate the need for both transcriptional and AS data in gene expression analyses. AS has influenced the evolution of the complex networks of regulation of gene expression and variation in AS contributed to adaptation of plants to their environment and therefore will impact strategies for improving plant and crop phenotypes.
在植物中，超过 60%的内含子基因发生可变剪接（AS）。当探索不同组织、发育阶段和环境条件下的 AS 时，这个数字将会增加。尽管 AS 对蛋白质复杂性的功能影响在植物中仍研究不足，但最近的例子表明其在调节植物过程中的重要性。AS 还调节转录本水平，与无义介导的衰变和无产物 mRNA 的产生相关联，这说明了在基因表达分析中既需要转录数据也需要 AS 数据。AS 影响了基因表达调控的复杂网络的进化，并且 AS 的变异促进了植物对环境的适应，因此将影响改善植物和作物表型的策略。
