School of Automation, University of Electronic Science and Technology of China, Chengdu 611731, China.
Med Phys. 2012 Jun;39(6):3299-318. doi: 10.1118/1.4718565.
Accurately segmenting breast tumors in ultrasound (US) images is a difficult problem due to their specular nature and appearance of sonographic tumors. The current paper presents a variant of the normalized cut (NCut) algorithm based on homogeneous patches (HP-NCut) for the segmentation of ultrasonic breast tumors.
A novel boundary-detection function is defined by combining texture and intensity information to find the fuzzy boundaries in US images. Subsequently, based on the precalculated boundary map, an adaptive neighborhood according to image location referred to as a homogeneous patch (HP) is proposed. HPs are guaranteed to spread within the same tissue region; thus, the statistics of primary features within the HPs is more reliable in distinguishing the different tissues and benefits subsequent segmentation. Finally, the fuzzy distribution of textons within HPs is used as final image features, and the segmentation is obtained using the NCut framework.
The HP-NCut algorithm was evaluated on a large dataset of 100 breast US images (50 benign and 50 malignant). The mean Hausdorff distance measure, the mean minimum Euclidean distance measure and similarity measure achieved 7.1 pixels, 1.58 pixels, and 86.67%, respectively, for benign tumors while those achieved 10.57 pixels, 1.98 pixels, and 84.41%, respectively, for malignant tumors.
The HP-NCut algorithm provided the improvement in accuracy and robustness compared with state-of-the-art methods. A conclusion that the HP-NCut algorithm is suitable for ultrasonic tumor segmentation problems can be drawn.
由于乳腺肿瘤的镜面特性和超声肿瘤的出现,准确分割超声(US)图像中的乳腺肿瘤是一个难题。本文提出了一种基于均匀补丁(HP-NCut)的归一化割(NCut)算法变体,用于超声乳腺肿瘤的分割。
通过结合纹理和强度信息定义了一种新的边界检测函数,以在 US 图像中找到模糊边界。随后,基于预计算的边界图,根据图像位置提出了一种称为均匀补丁(HP)的自适应邻域。HP 保证在同一组织区域内传播;因此,HP 内主要特征的统计在区分不同组织方面更可靠,有利于后续分割。最后,将 HP 内纹理的模糊分布用作最终图像特征,并使用 NCut 框架进行分割。
HP-NCut 算法在 100 个乳腺 US 图像(50 个良性和 50 个恶性)的大型数据集上进行了评估。良性肿瘤的平均 Hausdorff 距离度量、平均最小欧几里得距离度量和相似度量分别为 7.1 像素、1.58 像素和 86.67%,恶性肿瘤的分别为 10.57 像素、1.98 像素和 84.41%。
与最先进的方法相比,HP-NCut 算法在准确性和鲁棒性方面都有所提高。可以得出结论,HP-NCut 算法适用于超声肿瘤分割问题。