Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Cytoskeleton (Hoboken). 2012 Oct;69(10):700-9. doi: 10.1002/cm.21045. Epub 2012 Jul 3.
Cytokinesis shape change occurs through the interfacing of three modules, cell mechanics, myosin II-mediated contractile stress generation and sensing, and a control system of regulatory proteins, which together ensure flexibility and robustness. This integrated system then defines the stereotypical shape changes of successful cytokinesis, which occurs under a diversity of mechanical contexts and environmental conditions.
胞质分裂的形状变化是通过三个模块的相互作用实现的，这三个模块分别是细胞力学、肌球蛋白 II 介导的收缩力产生和感知，以及一个调节蛋白的控制系统，它们共同确保了灵活性和鲁棒性。这个集成系统定义了典型的成功胞质分裂的形状变化，这种变化发生在多种力学环境和环境条件下。
