Harvard School of Public Health, Boston, MA, USA.
Health Aff (Millwood). 2012 Jul;31(7):1459-69. doi: 10.1377/hlthaff.2012.0407.
Antiretroviral therapy for HIV may have important economic benefits for patients and their households. We quantified the impact of HIV treatment on employment status among HIV patients in rural South Africa who were enrolled in a public-sector HIV treatment program supported by the President's Emergency Plan for AIDS Relief. We linked clinical data from more than 2,000 patients in the treatment program with ten years of longitudinal socioeconomic data from a complete community-based population cohort of more than 30,000 adults residing in the clinical catchment area. We estimated the employment effects of HIV treatment in fixed-effects regressions. Four years after the initiation of antiretroviral therapy, employment among HIV patients had recovered to about 90 percent of baseline rates observed in the same patients three to five years before they started treatment. Many patients initiated treatment early enough that they were able to avoid any loss of employment due to HIV. These results represent the first estimates of employment recovery among HIV patients in a general population, relative to the employment levels that these patients had prior to job-threatening HIV illness and the decision to seek care. There are large economic benefits to HIV treatment. For some patients, further gains could be obtained from initiating antiretroviral therapy earlier, prior to HIV-related job loss.
抗逆转录病毒疗法可能会为 HIV 患者及其家庭带来重要的经济效益。我们量化了 HIV 治疗对在南非农村接受由总统艾滋病紧急救援计划支持的公共部门 HIV 治疗计划的 HIV 患者的就业状况的影响。我们将来自治疗计划中 2000 多名患者的临床数据与来自居住在临床服务区的 30000 多名成年人的完整社区人群队列的十年纵向社会经济数据进行了关联。我们在固定效应回归中估计了 HIV 治疗的就业影响。在开始接受抗逆转录病毒治疗四年后,HIV 患者的就业率已恢复到治疗前三到五年基线水平的约 90%。许多患者开始治疗的时间足够早,以至于他们能够避免因 HIV 而导致任何失业。这些结果代表了在一般人群中 HIV 患者的就业恢复情况的首次估计,与这些患者在面临威胁工作的 HIV 疾病和寻求治疗之前的就业水平相比。HIV 治疗带来了巨大的经济效益。对于某些患者来说,更早地开始抗逆转录病毒治疗,在与 HIV 相关的失业之前,可能会获得进一步的收益。