Golpour Masoud, Hosseini Seyed Hamzeh, Khademloo Mohammad, Ghasemi Maryam, Ebadi Aghdas, Koohkan Fatemeh, Shahmohammadi Soheila
Department of Dermatology, Booali Sina Hospital, Mazandaran University of Medical Sciences, Sari, Iran.
Dermatol Res Pract. 2012;2012:381905. doi: 10.1155/2012/381905. Epub 2012 Jul 16.
Background. Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. Psychological stress can exacerbate the disease. This study sought to investigate the depression and anxiety disorders among patients with psoriasis and control group. Method. In this hospital-based case-control study, One hundred patients with psoriasis (case) referred to the dermatology department and 100 patients with otolaryngology problems and dermatological healthy volunteers (control) who referred to the Otolaryngology Department of Bouali Sina Hospital in Sari, Iran, in 2007 were studied. Demographic characteristics were recorded. Beck Depression Inventory and Spielberger State-Trait Anxiety Scale I-II were administered to the patients in both groups. Data were analyzed using SPSS statistical software and descriptive statistical tests. Results. From One-hundred patients in each group, 44 (45%) were men. Depression score was 67% and 12% in psoriatic patients and control, respectively. The Beck depression scores of patients with psoriasis were significantly higher than scores of the control group (P < 0.05). Based on Spielberger State-Trait Anxiety Scale, anxiety was found in 45% of patients in case group and 18% of controls. Conclusion. The results revealed that psoriatic patients reported significantly higher degrees of depression and anxiety than controls. In addition, psoriatic women were more depressed than psoriatic men.
背景。银屑病是一种常见的、由基因决定的皮肤炎症性增殖性疾病。心理压力会加重该病。本研究旨在调查银屑病患者与对照组中的抑郁和焦虑障碍情况。方法。在这项基于医院的病例对照研究中，对2007年转诊至伊朗萨里市布阿利·西纳医院皮肤科的100例银屑病患者（病例组）以及转诊至该医院耳鼻喉科的100例有耳鼻喉科问题且皮肤健康的志愿者（对照组）进行了研究。记录人口统计学特征。对两组患者均使用贝克抑郁量表和斯皮尔伯格状态 - 特质焦虑量表I - II进行评估。使用SPSS统计软件和描述性统计检验对数据进行分析。结果。每组100例患者中，44例（45%）为男性。银屑病患者和对照组的抑郁得分分别为67%和12%。银屑病患者的贝克抑郁得分显著高于对照组（P < 0.05）。根据斯皮尔伯格状态 - 特质焦虑量表，病例组45%的患者存在焦虑，对照组为18%。结论。结果显示，银屑病患者报告的抑郁和焦虑程度显著高于对照组。此外，银屑病女性比男性更易抑郁。
