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供体人群中查加斯病感染的血清流行率。

Seroprevalence of Chagas infection in the donor population.

机构信息

Department of Medicine, University of Washington, Seattle, Washington, United States of America.

出版信息

PLoS Negl Trop Dis. 2012;6(7):e1771. doi: 10.1371/journal.pntd.0001771. Epub 2012 Jul 31.

Abstract

We retrospectively calculated the prevalence and epidemiologic characteristics of Chagas infection in the New York blood donor population over three years utilizing the New York Blood Center's database of the New York metropolitan area donor population. Seventy Trypanosoma cruzi positive donors were identified from among 876,614 donors over a 3-year period, giving an adjusted prevalence of 0.0083%, with 0.0080% in 2007, 0.0073% in 2008, and 0.0097% in 2009. When filtered only for self-described "Hispanic/Latino" donors, there were 52 Chagas positive donors in that 3-year period (among 105,122 self-described Hispanic donors) with an adjusted prevalence of 0.052%, with 0.055% in 2007, 0.047% in 2008, and 0.053% in 2009. In conclusion, we found a persistent population of patients with Chagas infection in the New York metropolitan area donor population. There was geographic localization of cases which aligned with Latin American immigration clusters.

摘要

我们利用纽约血液中心的纽约大都市区献血者数据库,回顾性地计算了三年内纽约献血者人群中查加斯病感染的流行率和流行病学特征。在三年内的 876614 名献血者中,发现了 70 名克氏锥虫阳性献血者,调整后的患病率为 0.0083%,其中 2007 年为 0.0080%,2008 年为 0.0073%,2009 年为 0.0097%。当仅对自我描述为“西班牙裔/拉丁裔”的献血者进行筛选时,在这三年期间,有 52 名查加斯阳性献血者(在 105122 名自我描述为西班牙裔的献血者中),调整后的患病率为 0.052%,其中 2007 年为 0.055%,2008 年为 0.047%,2009 年为 0.053%。总之,我们在纽约大都市区献血者人群中发现了持续存在的查加斯病感染患者群体。病例存在地域定位,与拉丁美洲移民群体一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7338/3409134/bc07042e2bef/pntd.0001771.g001.jpg

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