Bain R J, Tan L B, Murray R G, Davies M K, Littler W A
Department of Cardiovascular Medicine, University of Birmingham, East Birmingham Hospital, Bordesley Green East, England.
Eur J Appl Physiol Occup Physiol. 1990;61(1-2):112-8. doi: 10.1007/BF00236703.
Cardiac haemodynamics are deranged in chronic heart failure but fail to predict the exercise capacity of the patient. Cardiac power output is a descriptor of cardiac function derived from preload, blood pressure and cardiac output. Forty-one patients with moderately severe and severe chronic heart failure were exercised on a cycle ergometer to determine the relationship between traditional haemodynamics and cardiac power output and exercise capacity. Resting cardiac power output was no more predictive of exercise capacity than resting stroke-work index or resting cardiac index (r = 0.53, 0.61 and 0.51 respectively). Maximum cardiac power output and the ability to increase cardiac power output, however, were correlated with exercise capacity (r = 0.79 and 0.80). It is concluded that resting cardiac power output does not predict subsequent exercise capacity but that maximum cardiac power output and the ability to increase cardiac power output on stimulation are good descriptors of functional cardiac reserve.
慢性心力衰竭时心脏血流动力学紊乱,但无法预测患者的运动能力。心脏功率输出是一种源自前负荷、血压和心输出量的心脏功能描述指标。41例中度至重度慢性心力衰竭患者在自行车测力计上进行运动,以确定传统血流动力学与心脏功率输出及运动能力之间的关系。静息心脏功率输出对运动能力的预测性并不比静息每搏功指数或静息心指数更高(相关系数分别为0.53、0.61和0.51)。然而,最大心脏功率输出以及增加心脏功率输出的能力与运动能力相关(相关系数分别为0.79和0.80)。结论是,静息心脏功率输出不能预测随后的运动能力,但最大心脏功率输出以及刺激时增加心脏功率输出的能力是心脏功能储备的良好描述指标。