Bone Density Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019, USA.
J Clin Densitom. 2013 Jan-Mar;16(1):104-9. doi: 10.1016/j.jocd.2012.07.009. Epub 2012 Aug 16.
Whole-body vibration (WBV) augments the musculoskeletal effects of resistance exercise (RE). However, its acute effects on bone turnover markers (BTM) have not been determined. This study examined BTM responses to acute high-intensity RE and high-intensity RE with WBV (WBV+RE) in young women (n=10) taking oral contraceptives in a randomized, crossover repeated measures design. WBV+RE exposed subjects to 5 one-minute bouts of vibration (20 Hz, 3.38 peak-peak displacement, separated by 1 min of rest) before RE. Fasting blood samples were obtained before (Pre), immediately after WBV (PostVib), immediately after RE (IP), and 30-min after RE (P30). Bone alkaline phosphatase did not change at any time point. Tartrate-resistant acid phosphatase 5b significantly increased (p<0.05) from the Pre to PostVib, then decreased from IP to P30 for both conditions. C-terminal telopeptide of type I collagen (CTX) significantly decreased (p<0.05) from Pre to PostVib and from Pre to P30 only for WBV+RE. WBV+RE showed a greater decrease in CTX than RE (-12.6% ± 4.7% vs -1.13% ± 3.5%). In conclusion, WBV was associated with acute decreases in CTX levels not elicited with RE alone in young women.
全身振动（WBV）增强了抗阻运动（RE）对骨骼肌肉系统的影响。然而，其对骨转换标志物（BTM）的急性影响尚未确定。本研究采用随机交叉重复测量设计，在服用口服避孕药的年轻女性（n=10）中，检测了急性高强度 RE 和高强度 RE 联合 WBV（WBV+RE）对 BTM 的影响。WBV+RE 使受试者在 RE 前接受 5 次 1 分钟的振动（20 Hz，3.38 峰峰值位移，间隔 1 分钟休息）。在禁食状态下，分别在以下时间点采集血样：（Pre）、WBV 后即刻（PostVib）、RE 后即刻（IP）和 RE 后 30 分钟（P30）。骨碱性磷酸酶在任何时间点均未发生变化。抗酒石酸酸性磷酸酶 5b （TRACP-5b）在预测量至 WBV 后即刻显著增加（p<0.05），然后在 IP 至 P30 时两种条件下均显著降低。I 型胶原 C 端肽（CTX）在 WBV+RE 组从预测量至 WBV 后即刻以及从预测量至 P30 时均显著降低（p<0.05），而在 RE 组仅从预测量至 P30 时显著降低。与 RE 组相比，WBV+RE 组 CTX 降低幅度更大（-12.6% ± 4.7% vs -1.13% ± 3.5%）。总之，与单独 RE 相比，WBV 可引起年轻女性的 CTX 水平急性下降。
