Midwestern University Chicago College of Pharmacy, Downers Grove, IL 60515, USA.
Postgrad Med. 2012 Jul;124(4):84-94. doi: 10.3810/pgm.2012.07.2571.
Diabetes is one of the most costly and burdensome chronic diseases, and its therapy and management have become increasingly complex. The incidence of type 2 diabetes mellitus (T2DM), a multiorgan disorder, is increasing at an epidemic rate in the United States and worldwide. Despite numerous scientific and medical advances, less than half of the population with T2DM has achieved the American Diabetes Association-recommended glycated hemoglobin level goal of < 7%, which is necessary to optimally manage the disease to prevent and minimize complications. There are many patient- and clinician-determined barriers that hinder patients from achieving target blood glucose levels. Therefore, it is imperative for health care professionals who treat patients with T2DM (and those at risk for developing T2DM) to have an enhanced knowledge base of the current pathophysiology, treatment options, and clinical guidelines for T2DM and its related conditions.
糖尿病是最昂贵和负担最重的慢性病之一，其治疗和管理变得越来越复杂。在美国和全球范围内，多器官疾病 2 型糖尿病（T2DM）的发病率呈流行趋势不断上升。尽管在科学和医学方面取得了许多进步，但只有不到一半的 T2DM 患者达到了美国糖尿病协会推荐的糖化血红蛋白水平目标<7%，而这是最佳管理疾病以预防和最小化并发症所必需的。有许多由患者和临床医生确定的障碍会阻碍患者达到目标血糖水平。因此，治疗 T2DM（和有发展为 T2DM 风险的患者）的医疗保健专业人员必须增强对 T2DM 及其相关病症的当前病理生理学、治疗选择和临床指南的基本知识。
