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N-羧丁基壳聚糖的抗菌性能

Antimicrobial properties of N-carboxybutyl chitosan.

作者信息

Muzzarelli R, Tarsi R, Filippini O, Giovanetti E, Biagini G, Varaldo P E

机构信息

Institute of Biochemistry, Faculty of Medicine, University of Ancona, Italy.

出版信息

Antimicrob Agents Chemother. 1990 Oct;34(10):2019-23. doi: 10.1128/AAC.34.10.2019.

DOI:10.1128/AAC.34.10.2019
PMID:2291669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC171983/
Abstract

N-Carboxybutyl chitosan, a modified chitin of crustacean origin, displayed inhibitory, bactericidal, and candidacidal activities when tested against 298 cultures of various pathogens. Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations. The data are of importance in defining the suitability of N-carboxybutyl chitosan as a wound dressing.

摘要

N-羧丁基壳聚糖是一种源自甲壳类动物的改性几丁质，在针对298种不同病原体培养物进行测试时，表现出抑制、杀菌和杀念珠菌活性。电子显微镜检查显示，暴露于N-羧丁基壳聚糖的微生物细胞发生了明显的形态改变。这些数据对于确定N-羧丁基壳聚糖作为伤口敷料的适用性具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/7554c95ffa16/aac00066-0191-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/268567c06b7d/aac00066-0190-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/6b5434636fa9/aac00066-0190-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/2dacadbf0f9c/aac00066-0191-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/7554c95ffa16/aac00066-0191-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/268567c06b7d/aac00066-0190-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/6b5434636fa9/aac00066-0190-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/2dacadbf0f9c/aac00066-0191-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/397b/171983/7554c95ffa16/aac00066-0191-b.jpg

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