N-羧丁基壳聚糖的抗菌性能
Antimicrobial properties of N-carboxybutyl chitosan.
作者信息
Muzzarelli R, Tarsi R, Filippini O, Giovanetti E, Biagini G, Varaldo P E
机构信息
Institute of Biochemistry, Faculty of Medicine, University of Ancona, Italy.
出版信息
Antimicrob Agents Chemother. 1990 Oct;34(10):2019-23. doi: 10.1128/AAC.34.10.2019.
N-Carboxybutyl chitosan, a modified chitin of crustacean origin, displayed inhibitory, bactericidal, and candidacidal activities when tested against 298 cultures of various pathogens. Examination by electron microscopy showed that microbial cells exposed to N-carboxybutyl chitosan underwent marked morphological alterations. The data are of importance in defining the suitability of N-carboxybutyl chitosan as a wound dressing.
N-羧丁基壳聚糖是一种源自甲壳类动物的改性几丁质，在针对298种不同病原体培养物进行测试时，表现出抑制、杀菌和杀念珠菌活性。电子显微镜检查显示，暴露于N-羧丁基壳聚糖的微生物细胞发生了明显的形态改变。这些数据对于确定N-羧丁基壳聚糖作为伤口敷料的适用性具有重要意义。
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