Iida J, Une T, Ishihara C, Nishimura K, Tokura S, Mizukoshi N, Azuma I
Institute of Immunological Science, Hokkaido University, Sapporo, Japan.
Vaccine. 1987 Dec;5(4):270-4. doi: 10.1016/0264-410x(87)90150-2.
The efficacy of chitin derivatives on non-specific host resistance to Sendai virus and Escherichia coli infections was studied in mice. Seventy percent deacetylated chitin (DAC-70) and N-trimethylated DAC-70 [DAC-70(Me)3] showed protective activity against Sendai virus infection; however, carboxymethyl-chitin (CM-chitin) did not. DAC-70 also showed protective activity against E. coli infection.
