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本文引用的文献

1
Efficacy of the BioXtra dry mouth care system in the treatment of radiotherapy-induced xerostomia.BioXtra口干护理系统在治疗放疗引起的口腔干燥症中的疗效。
Support Care Cancer. 2007 Dec;15(12):1429-36. doi: 10.1007/s00520-006-0210-y. Epub 2007 Jan 18.
2
Different saliva substitutes for treatment of xerostomia following radiotherapy. A prospective crossover study.不同唾液替代品用于放疗后口干症的治疗。一项前瞻性交叉研究。
Strahlenther Onkol. 2005 Apr;181(4):231-6. doi: 10.1007/s00066-005-1333-7.
3
An update of the etiology and management of xerostomia.口干症的病因及治疗进展
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jan;97(1):28-46. doi: 10.1016/j.tripleo.2003.07.010.
4
Long-term oral Candida colonization, mucositis and salivary function after head and neck radiotherapy.头颈部放疗后的长期口腔念珠菌定植、黏膜炎和唾液功能
Support Care Cancer. 2003 Nov;11(11):717-21. doi: 10.1007/s00520-003-0506-0. Epub 2003 Aug 9.
5
Adverse drug reactions in the mouth.
Clin Dermatol. 2000 Sep-Oct;18(5):525-32. doi: 10.1016/s0738-081x(00)00143-7.
6
Low unstimulated salivary flow and subjective oral dryness: association with medication, anxiety, depression, and stress.静息唾液低分泌量与主观口腔干燥：与药物、焦虑、抑郁及压力的关联
J Dent Res. 2000 Sep;79(9):1652-8. doi: 10.1177/00220345000790090301.
7
A study of health and health related social problems in the geriatric population in a rural area of Tamil Nadu.泰米尔纳德邦农村地区老年人口健康及与健康相关社会问题的研究。
Indian J Public Health. 1998 Jan-Mar;42(1):7-8.
8
Relationship of medical status, medications, and salivary flow rates in adults of different ages.不同年龄成年人的健康状况、药物治疗与唾液流速之间的关系。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Feb;81(2):172-6. doi: 10.1016/s1079-2104(96)80410-0.
9
Subjective reports of oral dryness in an older adult population.老年人群口腔干燥的主观报告。
Community Dent Oral Epidemiol. 1993 Jun;21(3):165-8. doi: 10.1111/j.1600-0528.1993.tb00744.x.
10
Xerostomia. Part II: Relationship to nonoral symptoms, drugs, and diseases.口干症。第二部分：与非口腔症状、药物及疾病的关系。
Oral Surg Oral Med Oral Pathol. 1989 Oct;68(4):419-27. doi: 10.1016/0030-4220(89)90140-0.

老年人药物性口干：一项机构研究。

Drug induced xerostomia in elderly individuals: An institutional study.

作者信息

Shetty Shishir Ram, Bhowmick Sunanda, Castelino Renita, Babu Subhas

机构信息

Department of Oral Medicine and Radiology, AB Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India.

出版信息

Contemp Clin Dent. 2012 Apr;3(2):173-5. doi: 10.4103/0976-237X.96821.

DOI:10.4103/0976-237X.96821
PMID:22919217
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3425100/
Abstract

INTRODUCTION

With better health care facilities and nutritional levels the average life expectancy of Indian population has been on the rise over the years. Most of the geriatric population is under long-term medication.

AIM

The aim of this study was to evaluate the synergistic effect of multiple xerostomia drugs.

MATERIALS AND METHODS

Unstimulated saliva was measured in 60 geriatric patients, and xerostomia questionnaire and quality-of-life scale were also administered.

RESULTS

There was a very highly significant reduction in the salivary flow rates of patients under multiple xerostomia-inducing drugs.

CONCLUSION

The synergistic effect of the xerostomia inducing medication could be the possible factor responsible for reduced salivary flow in elderly individuals using such drugs.

摘要

引言

随着医疗保健设施和营养水平的提高，印度人口的平均预期寿命多年来一直在上升。大多数老年人口都在长期服药。

目的

本研究的目的是评估多种口干药物的协同作用。

材料与方法

对60名老年患者测量非刺激性唾液，并发放口干问卷和生活质量量表。

结果

服用多种导致口干药物的患者唾液流速显著降低。

结论

导致口干药物的协同作用可能是使用此类药物的老年人唾液分泌减少的原因。