Bali Akshay, Roy Maitrayee, Chikkannaiah Panduranga, Dhorigol Vijayalaxmi
Department of Pathology, Jawaharlal Nehru Medical College, Belgaum, India.
J Lab Physicians. 2012 Jan;4(1):53-5. doi: 10.4103/0974-2727.98677.
Clear cell sarcoma is a deep-seated, exceedingly rare aggressive tumor, typically involving the tendons and aponeuroses with melanocytic differentiation and a distinct genetic background. A primary dermal location is rarer. It exhibits histological, immunohistochemical, and ultrastructural similarities with the more common primary (or metastatic) malignant melanoma causing major diagnostic confusion. We describe a case of primary cutaneous clear cell sarcoma arising in the right lower extremity of a 40-year-old male patient.
透明细胞肉瘤是一种深部的、极其罕见的侵袭性肿瘤，通常累及肌腱和腱膜，具有黑素细胞分化及独特的遗传背景。原发性皮肤部位更为罕见。它在组织学、免疫组化和超微结构上与更常见的原发性（或转移性）恶性黑色素瘤相似，这导致了主要的诊断混淆。我们描述了一例发生在一名40岁男性患者右下肢的原发性皮肤透明细胞肉瘤病例。
