Department of Prosthodontics, College of Dentistry, Yonsei University, Seoul, Korea.
Implant Dent. 2012 Oct;21(5):415-21. doi: 10.1097/ID.0b013e31826a51f4.
Despite the substantial contribution of titanium implants in the field of dental and orthopedic reconstructive therapy, there is a crucial unaddressed question of why bone-implant contact does not reach the ideal 100%. This review article introduces the recently reported time-dependent reduction in osteoconductivity and other biological capabilities of titanium since processing. This phenomenon is defined as the biological aging of titanium and provides insight to significantly advance the understanding of osseointegration and to further improve implant surfaces in the future.
尽管钛植入物在牙科和骨科重建治疗领域做出了巨大贡献，但仍存在一个关键问题悬而未决，即为什么骨-植入物接触无法达到理想的 100%。本文综述了最近报道的钛在加工后其骨诱导性和其他生物学性能随时间降低的现象，将其定义为钛的生物学老化，并为深入了解骨整合以及未来进一步改善植入物表面提供了重要的见解。
