一种协同增强的 T(1)-T(2)双模态对比剂。
A synergistically enhanced T(1) -T(2) dual-modal contrast agent.
机构信息
State Key Laboratory of Physical Chemistry of Solid Surfaces, The Key Laboratory for Chemical Biology of Fujian Province and Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China.
出版信息
Adv Mater. 2012 Dec 4;24(46):6223-8. doi: 10.1002/adma.201203169. Epub 2012 Sep 13.
Abstract
Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1) and T(2) effects. GdIO nanoparticles have the unique property to be both T(1) and T(2) contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.
摘要
单分散的 Gd(2)O(3) 嵌入的氧化铁 (GdIO) 纳米粒子在外部磁场下可以相互增强局部磁场强度，从而协同增强 T(1)和 T(2)效应。GdIO 纳米粒子具有同时作为 T(1)和 T(2)对比剂的独特性质，有可能提高癌症诊断的准确性，特别是肝肿瘤的诊断准确性。
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