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沙门氏菌科霍乱血清型噬菌体 P1 介导的自然溶原化和转导作用

Natural lysogenization and transduction in Salmonella enterica serovar Choleraesuis by bacteriophage P1.

机构信息

Pontificia Universidad Católica de Valparaíso, Instituto de Biología, Laboratorio de Bacteriología, Av. Universidad 330, Campus Curauma, Valparaíso, Chile.

出版信息

Res Microbiol. 2013 Jan;164(1):1-5. doi: 10.1016/j.resmic.2012.09.004. Epub 2012 Sep 17.

DOI:10.1016/j.resmic.2012.09.004
PMID:22995628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3790573/
Abstract

It has been reported that bacteriophage P1 injects DNA into serovar Choleraesuis without evidence of productive infection. However, we found that P1 generates progeny and is capable of transduction in serovar Choleraesuis. This is not the case with other serovars of Salmonella enterica we tested. Therefore, P1 could play a role in serovar Choleraesuis evolution and contribute to its genetic manipulation and analysis.

摘要

据报道，噬菌体 P1 在没有生产性感染证据的情况下将 DNA 注入血清型霍乱弧菌。然而，我们发现 P1 可以产生后代并能够在血清型霍乱弧菌中进行转导。在我们测试的其他沙门氏菌血清型中则不是这样。因此，P1 可能在血清型霍乱弧菌的进化中发挥作用，并有助于其遗传操作和分析。

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