Faculty of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan.
Evid Based Complement Alternat Med. 2012;2012:173297. doi: 10.1155/2012/173297. Epub 2012 Sep 11.
Ginseng, an ancient and famous medicinal herb in the Orient, has been used as a valuable tonic and for the treatment of various diseases including hepatic disorders. Ginseng saponins, commonly known as ginsenosides, are principal constituents and have believed to be responsible for multiple ginseng health benefits. There are more 40 ginsenosides isolated from ginseng. To date, treatment options for common liver diseases such as cirrhosis, fatty liver, and chronic hepatitis remain problematic. In this regard, ginseng extracts and individual ginsenosides have shown a wide array of beneficial role in the regulation of regular liver functions and the treatment of liver disorders of acute/chronic hepatotoxicity, hepatitis, hepatic fibrosis/cirrhosis, hepatocellular carcinoma, and so on in various pathways and mechanisms. In this paper, we first outline the pharmacological effects of ginseng and ginsenosides on the liver functions.
人参是东方一种古老而著名的药用植物，被用作有价值的滋补品，并用于治疗各种疾病，包括肝脏疾病。人参皂苷，通常称为人参皂苷，是主要成分，被认为是人参多种健康益处的原因。从人参中已分离出 40 多种人参皂苷。迄今为止，肝硬化、脂肪肝和慢性肝炎等常见肝脏疾病的治疗选择仍然存在问题。在这方面，人参提取物和个别人参皂苷在调节正常肝功能和治疗急性/慢性肝毒性、肝炎、肝纤维化/肝硬化、肝癌等肝脏疾病方面表现出广泛的有益作用通过各种途径和机制。在本文中，我们首先概述了人参和人参皂苷对肝功能的药理作用。
