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大突尼斯地区人群的血脂异常:患病率及影响因素

Dyslipidemia in the Greater Tunis population: prevalence and determinants.

作者信息

Hadj-Taieb Sameh, Elasmi Monia, Hammami Mohamed Bassem, Marrakchi Rim, Amani Kallel, Omar Souheil, Sanhaji Haifa, Jemaa Riadh, Feki Moncef, Kaabachi Naziha

机构信息

Research Laboratory LR99ES11, Department of Biochemistry, Rabta Hospital and Faculty of Medicine of Tunis, El Manar University, Tunis, Tunisia.

出版信息

Clin Lab. 2012;58(7-8):763-70.

Abstract

BACKGROUND

Economic development and socio-demographic changes have led to increased frequency of cardiovascular disease and other chronic diseases in Tunisia.

OBJECTIVES

To assess the prevalence of different types of dyslipidemia and to examine their association with sociodemographic characteristics in the Greater Tunis population.

METHODS

The study included 2712 subjects (1228 men and 1484 women) aged 35-70 years, recruited during the years 2004 and 2005 from the Greater Tunis population. Hypercholesterolemia, hypertriglyceridemia, and low HDL cholesterol were defined according to the National Cholesterol Education Program-Adult Treatment Panel III.

RESULTS

The prevalence of hypercholesterolemia, hypertriglyceridemia, and low HDL cholesterol was 40.8% (34.9% in males and 45.8% in females; p < 0.001), 29.2% (31.1% in males and 27.6% in females; p < 0.05), and 21.2% (32.5% in males and 11.5% in females; p < 0.001), respectively. The prevalence was higher in urban than rural regions. Hypercholesterolemia was more frequent in illiterate women and in men with high education level.

CONCLUSIONS

Dyslipidemias are common in Tunisians, mainly in urban areas, in illiterate women as well as in men with high levels of education. Profound changes of life style and dietary habits of Tunisians are needed to reduce the risk of cardiovascular diseases.

摘要

背景

经济发展和社会人口结构变化导致突尼斯心血管疾病及其他慢性病的发病率上升。

目的

评估大突尼斯地区不同类型血脂异常的患病率,并研究其与社会人口学特征的关联。

方法

该研究纳入了2004年和2005年从大突尼斯地区招募的2712名35至70岁的受试者(1228名男性和1484名女性)。高胆固醇血症、高甘油三酯血症和低高密度脂蛋白胆固醇血症根据美国国家胆固醇教育计划成人治疗组第三次报告进行定义。

结果

高胆固醇血症、高甘油三酯血症和低高密度脂蛋白胆固醇血症的患病率分别为40.8%(男性为34.9%,女性为45.8%;p<0.001)、29.2%(男性为31.1%,女性为27.6%;p<0.05)和21.2%(男性为32.5%,女性为11.5%;p<0.001)。城市地区的患病率高于农村地区。文盲女性和高学历男性中高胆固醇血症更为常见。

结论

血脂异常在突尼斯人中很常见,主要发生在城市地区、文盲女性以及高学历男性中。突尼斯人需要深刻改变生活方式和饮食习惯以降低心血管疾病风险。

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