Alkhater Suzan A
Department of Pediatrics, King Fahd Hospital of the University, Al-Khobar, Saudi Arabia.
J Family Community Med. 2009 Sep;16(3):77-82.
Children with a history of recurrent, severe, or unusual infections present a diagnostic challenge. It is important to maintain a high index of suspicion for the diagnosis of immunodeficiency, for early diagnosis and treatment can improve outcome. Differentiation between infections caused by common risk factors, or immune dysfunction should be based on a detailed history and physical examination and, if indicated, followed by appropriate laboratory studies. This paper aims at providing guidelines for the evaluation of children with recurrent infections. It provides an overview of the diagnostic approach including important details required from the history, physical examination, and an appropriate choice of screening test to be ordered.
有反复、严重或不寻常感染病史的儿童面临诊断挑战。对免疫缺陷的诊断保持高度怀疑指数很重要，因为早期诊断和治疗可改善预后。由常见风险因素或免疫功能障碍引起的感染之间的鉴别应基于详细的病史和体格检查，如有必要，随后进行适当的实验室检查。本文旨在为评估反复感染儿童提供指导方针。它概述了诊断方法，包括病史、体格检查所需的重要细节以及要安排的筛查试验的适当选择。
