Pela Ivana
Department of Women's and Children's Health Sciences, University of Florence, Florence, Italy.
Clin Cases Miner Bone Metab. 2012 May;9(2):112-7. Epub 2012 Sep 30.
Recently a number of studies have reported worldwide recrudescence of biochemical and clinical rickets, despite continuous revisions of the experts about the adequate intake of vitamin D for infants and children to maintain an adequate 25-hydroxyvitamin D status and assure the achievement of peak bone mass during the growth. The aim of this review is to illustrate the current opinions and controversies about what should be considered the normal range for serum 25-hydroxyvitamin D concentrations and which doses of vitamin D supplements should be recommended in the various pediatric ages and in different contests as climatic regions, colour of skin and sunlight exposure.
最近，一些研究报告称，尽管专家们不断修订婴儿和儿童维生素D的充足摄入量，以维持足够的25-羟基维生素D水平并确保在生长过程中达到峰值骨量，但全球范围内仍出现了生化性和临床性佝偻病的复发。本综述的目的是阐明当前关于血清25-羟基维生素D浓度的正常范围应如何界定，以及在不同的儿科年龄段、不同环境（如气候区域、肤色和阳光照射情况）下应推荐何种剂量的维生素D补充剂的观点和争议。
