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几丁质诱导土生链霉菌 A3(2)次级代谢途径基因表达。

Chitin-induced gene expression in secondary metabolic pathways of Streptomyces coelicolor A3(2) grown in soil.

机构信息

Environmental Biofunction Division, National Institute for Agro-Environmental Sciences, Tsukuba, Ibaraki, Japan.

出版信息

Appl Environ Microbiol. 2013 Jan;79(2):707-13. doi: 10.1128/AEM.02217-12. Epub 2012 Nov 2.

DOI:10.1128/AEM.02217-12
PMID:23124229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3553787/
Abstract

Microarray analyses revealed that the expression of genes for secondary metabolism together with that of primary metabolic genes was induced by chitin in autoclaved soil cultures of Streptomyces coelicolor A3(2). The data also indicated that DasR was involved in the regulation of gene expression for chitin catabolism, secondary metabolism, and stress responses.

摘要

微阵列分析显示,几丁质诱导了链霉菌 A3(2)的高压灭菌土壤培养物中次级代谢基因和初级代谢基因的表达。数据还表明,DasR 参与了几丁质分解代谢、次级代谢和应激反应的基因表达调控。

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本文引用的文献

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Chitin stimulates production of the antibiotic andrimid in a Vibrio coralliilyticus strain.几丁质刺激珊瑚弧菌菌株产生抗生素安比霉素。
Environ Microbiol Rep. 2011 Oct;3(5):559-64. doi: 10.1111/j.1758-2229.2011.00259.x. Epub 2011 May 9.
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Functional analysis of the N-acetylglucosamine metabolic genes of Streptomyces coelicolor and role in control of development and antibiotic production.链霉菌 N-乙酰葡萄糖胺代谢基因的功能分析及其在发育和抗生素产生调控中的作用。
J Bacteriol. 2012 Mar;194(5):1136-44. doi: 10.1128/JB.06370-11. Epub 2011 Dec 22.
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A survey of the cellular responses in Pseudomonas putida KT2440 growing in sterilized soil by microarray analysis.利用基因芯片分析研究在灭菌土壤中生长的恶臭假单胞菌 KT2440 的细胞反应。
FEMS Microbiol Ecol. 2011 Nov;78(2):220-32. doi: 10.1111/j.1574-6941.2011.01146.x. Epub 2011 Jul 4.
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High expression levels of chitinase genes in Streptomyces coelicolor A3(2) grown in soil.链霉菌 A3(2)在土壤中生长时几丁质酶基因的高表达水平。
FEMS Microbiol Ecol. 2011 Sep;77(3):623-35. doi: 10.1111/j.1574-6941.2011.01143.x. Epub 2011 Jul 4.
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Making informed choices about microarray data analysis.对微阵列数据分析做出明智的选择。
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The complex extracellular biology of Streptomyces.链霉菌复杂的细胞外生物学。
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Chapter 5. Applying the genetics of secondary metabolism in model actinomycetes to the discovery of new antibiotics.第5章:将模式放线菌中次生代谢的遗传学应用于新抗生素的发现
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Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by Streptomyces coelicolor A3(2) in response to salt and heat stresses.天蓝色链霉菌A3(2)在盐胁迫和热胁迫下对相容性溶质四氢嘧啶和5-羟基四氢嘧啶的合成与摄取
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Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces.feast or famine:全局调控因子DasR将营养应激与链霉菌的抗生素生产联系起来。
EMBO Rep. 2008 Jul;9(7):670-5. doi: 10.1038/embor.2008.83. Epub 2008 May 30.
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