Environmental Biofunction Division, National Institute for Agro-Environmental Sciences, Tsukuba, Ibaraki, Japan.
Appl Environ Microbiol. 2013 Jan;79(2):707-13. doi: 10.1128/AEM.02217-12. Epub 2012 Nov 2.
Microarray analyses revealed that the expression of genes for secondary metabolism together with that of primary metabolic genes was induced by chitin in autoclaved soil cultures of Streptomyces coelicolor A3(2). The data also indicated that DasR was involved in the regulation of gene expression for chitin catabolism, secondary metabolism, and stress responses.
微阵列分析显示,几丁质诱导了链霉菌 A3(2)的高压灭菌土壤培养物中次级代谢基因和初级代谢基因的表达。数据还表明,DasR 参与了几丁质分解代谢、次级代谢和应激反应的基因表达调控。