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实验室接触血液中生物危害剂的可能性。

Potential for laboratory exposures to biohazardous agents found in blood.

作者信息

Evans M R, Henderson D K, Bennett J E

机构信息

Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892.

出版信息

Am J Public Health. 1990 Apr;80(4):423-7. doi: 10.2105/ajph.80.4.423.

DOI:10.2105/ajph.80.4.423
PMID:2316762
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1404560/
Abstract

The magnitude of risk for occupational exposures to biohazardous agents found in blood was assessed by 800 environmental samples taken from a total of 10 clinical and research laboratories at the National Institutes of Health (NIH). Thirty-one samples from 11 work stations in three laboratories contained hepatitis B virus surface antigen (HBsAg). Observations of workers indicated that environmental contamination arose from several sources. Among the 11 work stations with HBsAg environmental samples, eight had high work loads, seven had inappropriate behaviors, and nine had flawed laboratory techniques. This information suggests that a multifactorial approach is needed to minimize the risk of laboratory-associated infections.

摘要

通过从美国国立卫生研究院(NIH)的10个临床和研究实验室采集的800份环境样本,评估了职业接触血液中生物危害剂的风险程度。来自三个实验室11个工作站的31份样本中含有乙型肝炎病毒表面抗原(HBsAg)。对工作人员的观察表明,环境污染源于多个来源。在11个有HBsAg环境样本的工作站中,8个工作量大,7个存在不当行为,9个实验室技术存在缺陷。这些信息表明,需要采取多因素方法来尽量降低实验室相关感染的风险。

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本文引用的文献

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Hepatitis B as a hazard to laboratory staff: a re-appraisal.乙肝对实验室工作人员的危害:重新评估
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Letter: Hepatitis-B antigen on environmental surfaces.信函:环境表面的乙肝抗原
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Risk of nosocomial infection with human T-cell lymphotropic virus type III/lymphadenopathy-associated virus in a large cohort of intensively exposed health care workers.大量密切接触的医护人员感染人类Ⅲ型嗜T细胞病毒/淋巴结病相关病毒的医院感染风险。
Ann Intern Med. 1986 May;104(5):644-7. doi: 10.7326/0003-4819-104-5-644.
10
Prevalence of antibody to human immunodeficiency virus and hepatitis B surface antigen in blood samples submitted to a hospital laboratory. Implications for handling specimens.送至医院实验室的血液样本中人类免疫缺陷病毒抗体和乙型肝炎表面抗原的流行情况。对样本处理的影响。
JAMA. 1987 Dec 18;258(23):3395-7.