School of Public Health, China Medical University, Shenyang, People's Republic of China.
PLoS One. 2012;7(11):e51137. doi: 10.1371/journal.pone.0051137. Epub 2012 Nov 30.
In Western countries, ultraviolet (UV)-induced skin cancer has been studied extensively regarding the high incidence of skin cancers in the white population; however, for people of color, cataracts are the main public health issue in relation to increased ambient ultraviolet radiation (UVR). To our knowledge, few studies have been conducted examining the relationship between cataracts and ambient UVR in China. In this study, we aimed to explore the relationship between and the factors influencing the disability prevalence of cataracts and annual ambient erythemal UVR exposure in 31 regions of China. The data used to determine the disability prevalence of cataracts was obtained from the Second China National Sample Survey on Disability. The regional annual erythemal UVR was calculated using Geographic Information System (GIS) methods based on data from the National Aeronautics and Space Administration (NASA) database. The relationship between the disability prevalence of cataracts and the annual ambient erythemal UVR was examined by using logistic regression. Both the age-standardized disability prevalence of cataracts (OR = 3.97, 95%CI 1.30-12.13, per 100KJ/m(2) increase in annual ambient erythemal UVR) and the disability prevalence of cataracts among a population ≥65 years old (OR = 3.97, 95%CI 1.30-12.13, per 100KJ/m(2) increase in annual ambient erythemal UVR) were higher in association with higher ambient erythemal UVR. Regions with higher urbanization and educational levels had lower disability prevalence of cataracts. We found positive associations of the age-standardized disability prevalence of cataracts and the disability prevalence of cataracts among a population ≥65 years old with ambient erythemal UVR in 31 regions of China.
在西方国家,由于白种人群皮肤癌发病率较高,紫外线(UV)诱发的皮肤癌已得到广泛研究;然而,对于有色人种而言,白内障是与环境紫外线辐射(UVR)增加相关的主要公共卫生问题。据我们所知,在中国,很少有研究探讨白内障与环境 UVR 之间的关系。在这项研究中,我们旨在探讨白内障的发病率及其影响因素与中国 31 个地区白内障致盲患病率和年环境红斑 UVR 暴露量之间的关系。用于确定白内障致盲患病率的数据来自第二次中国全国残疾人抽样调查。利用地理信息系统(GIS)方法,根据美国国家航空航天局(NASA)数据库的数据,计算出各地区的年红斑 UVR。利用 logistic 回归分析白内障致盲患病率与年环境红斑 UVR 之间的关系。年龄标准化的白内障致盲患病率(OR=3.97,95%CI1.30-12.13,每年每增加 100KJ/m(2)环境红斑 UVR)和≥65 岁人群的白内障致盲患病率(OR=3.97,95%CI1.30-12.13,每年每增加 100KJ/m(2)环境红斑 UVR)均与较高的环境红斑 UVR 呈正相关。城市化水平和教育水平较高的地区白内障致盲患病率较低。我们发现,在中国 31 个地区,年龄标准化的白内障致盲患病率和≥65 岁人群的白内障致盲患病率与环境红斑 UVR 呈正相关。