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用于医疗应用的生物相容氧化铁纳米粒子的化学设计。

Chemical design of biocompatible iron oxide nanoparticles for medical applications.

机构信息

Center for Nanoparticle Research, Institute for Basic Science (IBS) and School of Chemical and Biological Engineering, Seoul National University, Seoul 151-742, Korea.

出版信息

Small. 2013 May 27;9(9-10):1450-66. doi: 10.1002/smll.201202111. Epub 2012 Dec 11.

DOI:10.1002/smll.201202111
PMID:23233377
Abstract

Iron oxide nanoparticles are one of the most versatile and safe nanomaterials used in medicine. Recent progress in nanochemistry enables fine control of the size, crystallinity, uniformity, and surface properties of iron oxide nanoparticles. In this review, the synthesis of chemically designed biocompatible iron oxide nanoparticles with improved quality and reduced toxicity is discussed for use in diverse biomedical applications.

摘要

氧化铁纳米粒子是医学中应用最广泛、最安全的纳米材料之一。纳米化学的最新进展使得能够精细控制氧化铁纳米粒子的尺寸、结晶度、均匀性和表面性质。在本文综述中,讨论了用于各种生物医学应用的具有改进质量和降低毒性的化学设计的生物相容性氧化铁纳米粒子的合成。

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